User profiles for Hongda Wang

Hongda Wang

Research Scientist at Pictor Labs; Ph.D. at UCLA
Verified email at ucla.edu
Cited by 3284

Deep learning enables cross-modality super-resolution in fluorescence microscopy

H Wang, Y Rivenson, Y Jin, Z Wei, R Gao… - Nature …, 2019 - nature.com
We present deep-learning-enabled super-resolution across different fluorescence
microscopy modalities. This data-driven approach does not require numerical modeling of the …

The structure and function of cell membranes examined by atomic force microscopy and single-molecule force spectroscopy

Y Shan, H Wang - Chemical Society Reviews, 2015 - pubs.rsc.org
The cell membrane is one of the most complicated biological complexes, and long-term fierce
debates regarding the cell membrane persist because of technical hurdles. With the rapid …

[HTML][HTML] Early detection and classification of live bacteria using time-lapse coherent imaging and deep learning

H Wang, H Ceylan Koydemir, Y Qiu, B Bai… - Light: Science & …, 2020 - nature.com
Early identification of pathogenic bacteria in food, water, and bodily fluids is very important
and yet challenging, owing to sample complexities and large sample volumes that need to be …

Deep learning microscopy

Y Rivenson, Z Göröcs, H Günaydin, Y Zhang, H Wang… - Optica, 2017 - opg.optica.org
We demonstrate that a deep neural network can significantly improve optical microscopy,
enhancing its spatial resolution over a large field of view and depth of field. After its training, …

Virtual histological staining of unlabelled tissue-autofluorescence images via deep learning

Y Rivenson, H Wang, Z Wei, K de Haan… - Nature biomedical …, 2019 - nature.com
The histological analysis of tissue samples, widely used for disease diagnosis, involves
lengthy and laborious tissue preparation. Here, we show that a convolutional neural network …

[HTML][HTML] Progress in the correlative atomic force microscopy and optical microscopy

L Zhou, M Cai, T Tong, H Wang - Sensors, 2017 - mdpi.com
Atomic force microscopy (AFM) has evolved from the originally morphological imaging
technique to a powerful and multifunctional technique for manipulating and detecting the …

Single-molecule recognition imaging microscopy

C Stroh, H Wang, R Bash, B Ashcroft… - Proceedings of the …, 2004 - National Acad Sciences
Atomic force microscopy is a powerful and widely used imaging technique that can visualize
single molecules and follow processes at the single-molecule level both in air and in …

The role of CD47-SIRPα immune checkpoint in tumor immune evasion and innate immunotherapy

Z Li, Y Li, J Gao, Y Fu, P Hua, Y Jing, M Cai, H Wang… - Life Sciences, 2021 - Elsevier
As a transmembrane protein, CD47 plays an important role in mediating cell proliferation,
migration, phagocytosis, apoptosis, immune homeostasis, inhibition of NO signal transduction …

Three-dimensional virtual refocusing of fluorescence microscopy images using deep learning

Y Wu, Y Rivenson, H Wang, Y Luo, E Ben-David… - Nature …, 2019 - nature.com
We demonstrate that a deep neural network can be trained to virtually refocus a two-dimensional
fluorescence image onto user-defined three-dimensional (3D) surfaces within the …

Deep learning enhanced mobile-phone microscopy

Y Rivenson, H Ceylan Koydemir, H Wang, Z Wei… - Acs …, 2018 - ACS Publications
Mobile phones have facilitated the creation of field-portable, cost-effective imaging and
sensing technologies that approach laboratory-grade instrument performance. However, the …