Hepcidin is a peptide that regulates iron homeostasis by inhibiting iron absorption by the
small intestine and release of iron from macrophages. Its production is stimulated by iron …

Recently, it has been suggested that hepcidin, a peptide involved in iron homeostasis, is
regulated by bone morphogenetic proteins (BMPs), apparently by binding to hemojuvelin (Hjv) …

The antimicrobial peptide hepcidin appears to play a central role in the regulation of iron
homeostasis. In intact animals, iron overload or the injection of lipopolysaccharide (LPS) …

Chest pain is a leading reason patients seek medical evaluation. While assays to detect
myocyte death are used to diagnose a heart attack (acute myocardial infarction, AMI), there is no …

Hepcidin, the master regulator of enteric iron absorption, is controlled by the opposing
effects of pathways activated in response to iron excess or iron attenuation. Iron excess is …

Hepcidin is a major regulator of iron homeostasis. Hepcidin expression is upregulated by
inflammatory cytokines, particularly interleukin (IL)‐6 and even more potently by the bone …

Cell surface proteins Hfe, Tfr2, hemojuvelin and Tmprss6 play key roles in iron homeostasis.
Hfe and Tfr2 induce transcription of hepcidin, a small peptide that promotes the degradation …

The endocannabinoid system is a highly conserved and ubiquitous signalling pathway with
broad-ranging effects. Despite critical pathway functions, gene variants have not previously …

Hepcidin is an acute-phase response antimicrobial peptide that has emerged as a central
regulator of iron absorption. Circulating hepcidin levels have been shown to affect iron uptake, …

Background: Alcoholic liver disease is associated with increased hepatic iron accumulation.
The liver‐derived peptide hepcidin is the central regulator of iron homeostasis and recent …