User profiles for Hongzhu Cui

Hongzhu Cui

Staff Software Scientist, Thermo Fisher Scientific
Verified email at thermofisher.com
Cited by 717

[HTML][HTML] Structural genomics of SARS-CoV-2 indicates evolutionary conserved functional regions of viral proteins

S Srinivasan, H Cui, Z Gao, M Liu, S Lu, W Mkandawire… - Viruses, 2020 - mdpi.com
During its first two and a half months, the recently emerged 2019 novel coronavirus, SARS-CoV-2,
has already infected over one-hundred thousand people worldwide and has taken …

The variation game: Cracking complex genetic disorders with NGS and omics data

H Cui, A Dhroso, N Johnson, D Korkin - Methods, 2015 - Elsevier
Tremendous advances in Next Generation Sequencing (NGS) and high-throughput omics
methods have brought us one step closer towards mechanistic understanding of the complex …

Decentralized control of collaborative redundant manipulators with partial command coverage via locally connected recurrent neural networks

S Li, H Cui, Y Li, B Liu, Y Lou - Neural Computing and Applications, 2013 - Springer
This paper studies the decentralized control of multiple redundant manipulators for the
cooperative task execution problem. Different from existing work with assumptions that all …

[HTML][HTML] ATAV: a comprehensive platform for population-scale genomic analyses

Z Ren, G Povysil, JA Hostyk, H Cui, N Bhardwaj… - BMC …, 2021 - Springer
Background A common approach for sequencing studies is to do joint-calling and store
variants of all samples in a single file. If new samples are continually added or controls are re-…

Structural genomics and interactomics of 2019 Wuhan novel coronavirus, 2019-nCoV, indicate evolutionary conserved functional regions of viral proteins

H Cui, Z Gao, M Liu, S Lu, S Mo, W Mkandawire… - biorxiv, 2020 - biorxiv.org
During its first month, the recently emerged 2019 Wuhan novel coronavirus (2019-nCoV)
has already infected many thousands of people in mainland China and worldwide and took …

[HTML][HTML] Finding shortest and nearly shortest path nodes in large substantially incomplete networks by hyperbolic mapping

M Kitsak, A Ganin, A Elmokashfi, H Cui… - Nature …, 2023 - nature.com
Dynamic processes on networks, be it information transfer in the Internet, contagious spreading
in a social network, or neural signaling, take place along shortest or nearly shortest paths…

Open community challenge reveals molecular network modules with key roles in diseases

…, S Choobdar, L Cowen, J Crawford, H Cui… - bioRxiv, 2018 - biorxiv.org
Identification of modules in molecular networks is at the core of many current analysis
methods in biomedical research. However, how well different approaches identify disease-…

Boosting gene expression clustering with system-wide biological information: a robust autoencoder approach

H Cui, C Zhou, X Dai, Y Liang… - … Biology and Drug …, 2020 - inderscienceonline.com
Hongzhu Cui and Dmitry Korkin analysed the results. Randy Paffenroth supervised the work
… Dmitry Korkin directed the study and supervised the work of Hongzhu Cui. Hongzhu Cui

[HTML][HTML] The Extent of Edgetic Perturbations in the Human Interactome Caused by Population-Specific Mutations

H Cui, S Srinivasan, Z Gao, D Korkin - Biomolecules, 2023 - mdpi.com
Until recently, efforts in population genetics have been focused primarily on people of European
ancestry. To attenuate this bias, global population studies, such as the 1000 Genomes …

[HTML][HTML] Enriching human interactome with functional mutations to detect high-impact network modules underlying complex diseases

H Cui, S Srinivasan, D Korkin - Genes, 2019 - mdpi.com
Rapid progress in high-throughput -omics technologies moves us one step closer to the
datacalypse in life sciences. In spite of the already generated volumes of data, our knowledge of …