User profiles for Hongzhu Cui
Hongzhu CuiStaff Software Scientist, Thermo Fisher Scientific Verified email at thermofisher.com Cited by 717 |
[HTML][HTML] Structural genomics of SARS-CoV-2 indicates evolutionary conserved functional regions of viral proteins
During its first two and a half months, the recently emerged 2019 novel coronavirus, SARS-CoV-2,
has already infected over one-hundred thousand people worldwide and has taken …
has already infected over one-hundred thousand people worldwide and has taken …
The variation game: Cracking complex genetic disorders with NGS and omics data
Tremendous advances in Next Generation Sequencing (NGS) and high-throughput omics
methods have brought us one step closer towards mechanistic understanding of the complex …
methods have brought us one step closer towards mechanistic understanding of the complex …
Decentralized control of collaborative redundant manipulators with partial command coverage via locally connected recurrent neural networks
This paper studies the decentralized control of multiple redundant manipulators for the
cooperative task execution problem. Different from existing work with assumptions that all …
cooperative task execution problem. Different from existing work with assumptions that all …
[HTML][HTML] ATAV: a comprehensive platform for population-scale genomic analyses
Background A common approach for sequencing studies is to do joint-calling and store
variants of all samples in a single file. If new samples are continually added or controls are re-…
variants of all samples in a single file. If new samples are continually added or controls are re-…
Structural genomics and interactomics of 2019 Wuhan novel coronavirus, 2019-nCoV, indicate evolutionary conserved functional regions of viral proteins
During its first month, the recently emerged 2019 Wuhan novel coronavirus (2019-nCoV)
has already infected many thousands of people in mainland China and worldwide and took …
has already infected many thousands of people in mainland China and worldwide and took …
[HTML][HTML] Finding shortest and nearly shortest path nodes in large substantially incomplete networks by hyperbolic mapping
Dynamic processes on networks, be it information transfer in the Internet, contagious spreading
in a social network, or neural signaling, take place along shortest or nearly shortest paths…
in a social network, or neural signaling, take place along shortest or nearly shortest paths…
Open community challenge reveals molecular network modules with key roles in diseases
…, S Choobdar, L Cowen, J Crawford, H Cui… - bioRxiv, 2018 - biorxiv.org
Identification of modules in molecular networks is at the core of many current analysis
methods in biomedical research. However, how well different approaches identify disease-…
methods in biomedical research. However, how well different approaches identify disease-…
Boosting gene expression clustering with system-wide biological information: a robust autoencoder approach
… Hongzhu Cui and Dmitry Korkin analysed the results. Randy Paffenroth supervised the work
… Dmitry Korkin directed the study and supervised the work of Hongzhu Cui. Hongzhu Cui …
… Dmitry Korkin directed the study and supervised the work of Hongzhu Cui. Hongzhu Cui …
[HTML][HTML] The Extent of Edgetic Perturbations in the Human Interactome Caused by Population-Specific Mutations
Until recently, efforts in population genetics have been focused primarily on people of European
ancestry. To attenuate this bias, global population studies, such as the 1000 Genomes …
ancestry. To attenuate this bias, global population studies, such as the 1000 Genomes …
[HTML][HTML] Enriching human interactome with functional mutations to detect high-impact network modules underlying complex diseases
Rapid progress in high-throughput -omics technologies moves us one step closer to the
datacalypse in life sciences. In spite of the already generated volumes of data, our knowledge of …
datacalypse in life sciences. In spite of the already generated volumes of data, our knowledge of …