[PDF][PDF] Immunogenicity of standard and extended dosing intervals of BNT162b2 mRNA vaccine
…, H Abuelgasim, E Adland, S Adlou, HD Akther… - Cell, 2021 - cell.com
Extension of the interval between vaccine doses for the BNT162b2 mRNA vaccine was
introduced in the United Kingdom to accelerate population coverage with a single dose. At this …
introduced in the United Kingdom to accelerate population coverage with a single dose. At this …
[PDF][PDF] TCR and inflammatory signals tune human MAIT cells to exert specific tissue repair and effector functions
T Leng, HD Akther, CP Hackstein, K Powell, T King… - Cell reports, 2019 - cell.com
MAIT cells are an unconventional T cell population that can be activated through both TCR-dependent
and TCR-independent mechanisms. Here, we examined the impact of …
and TCR-independent mechanisms. Here, we examined the impact of …
[HTML][HTML] Treatment of COVID-19 with remdesivir in the absence of humoral immunity: a case report
…, EJM Toonen, CP Hackstein, HD Akther… - Nature …, 2020 - nature.com
The response to the coronavirus disease 2019 (COVID-19) pandemic has been hampered
by lack of an effective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
by lack of an effective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
[HTML][HTML] T-cell and antibody responses to first BNT162b2 vaccine dose in previously infected and SARS-CoV-2-naive UK health-care workers: a multicentre …
Background Previous infection with SARS-CoV-2 affects the immune response to the first
dose of the SARS-CoV-2 vaccine. We aimed to compare SARS-CoV-2-specific T-cell and …
dose of the SARS-CoV-2 vaccine. We aimed to compare SARS-CoV-2-specific T-cell and …
[HTML][HTML] T cell assays differentiate clinical and subclinical SARS-CoV-2 infections from cross-reactive antiviral responses
…, M Pace, A Brown, E Adland, K Adair, HD Akhter… - Nature …, 2021 - nature.com
Identification of protective T cell responses against SARS-CoV-2 requires distinguishing
people infected with SARS-CoV-2 from those with cross-reactive immunity to other …
people infected with SARS-CoV-2 from those with cross-reactive immunity to other …
[HTML][HTML] A conserved population of MHC II-restricted, innate-like, commensal-reactive T cells in the gut of humans and mice
Interactions with commensal microbes shape host immunity on multiple levels and play a
pivotal role in human health and disease. Tissue-dwelling, antigen-specific T cells are poised …
pivotal role in human health and disease. Tissue-dwelling, antigen-specific T cells are poised …
Evolution of long-term hybrid immunity in healthcare workers after different COVID-19 vaccination regimens: a longitudinal observational cohort study
…, H Abuelgasim, E Adland, Z Ahmed, HD Akther… - MedRxiv, 2022 - medrxiv.org
Both infection and vaccination, alone or in combination, generate antibody and T cell
responses against SARS-CoV-2. However, the maintenance of such responses – and hence …
responses against SARS-CoV-2. However, the maintenance of such responses – and hence …
Obesity Differs from Diabetes Mellitus in Antibody and T Cell Responses Post COVID-19 Recovery
…, N Hassan, CP Hackstein, S Adele, HD Akther… - medRxiv, 2023 - medrxiv.org
Objective: Obesity and type 2 diabetes (DM) are risk factors for severe COVID-19 outcomes,
which disproportionately affect South Asian populations. This study aims to investigate the …
which disproportionately affect South Asian populations. This study aims to investigate the …
Obesity Differs from Diabetes Mellitus in Antibody and T Cell Responses Post COVID-19 Recovery (preprint)
…, N Hassan, CP Hackstein, S Adele, HD Akther… - 2023 - pesquisa.bvsalud.org
Objective: Obesity and type 2 diabetes (DM) are risk factors for severe COVID-19 outcomes,
which disproportionately affect South Asian populations. This study aims to investigate the …
which disproportionately affect South Asian populations. This study aims to investigate the …
Unconventional functions of MR1 restricted T-cells
H Delowar Akther - 2022 - ora.ox.ac.uk
The non-polymorphic MHC class I-related protein 1 (MR1) is an antigen presenting receptor
that displays endogenous or microbial-derived metabolic intermediates. The commensal …
that displays endogenous or microbial-derived metabolic intermediates. The commensal …