Mutations in the GBA1 gene are the most common genetic risk factor for Parkinson's disease
(PD) and dementia with Lewy bodies (DLB). GBA1 encodes the lysosomal lipid hydrolase …

The 3-dimensional microstructure of a porous electrode from a lithium-ion battery has been
characterized for the first time. We use X-ray tomography to reconstruct a 43×348×478μm …

Pulmonary arterial hypertension (PAH) is a rare disorder with a poor prognosis. Deleterious
variation within components of the transforming growth factor-β pathway, particularly the …

Rationale: Recently, rare heterozygous mutations in GDF2 were identified in patients with
pulmonary arterial hypertension (PAH). GDF2 encodes the circulating BMP (bone …

Fire regimes in North American forests are diverse and modern fire records are often too
short to capture important patterns, trends, feedbacks, and drivers of variability. Tree‐ring fire …

Echocardiography is the mainstay in screening for pulmonary hypertension (PH). International
guidelines suggest echocardiographic parameters for suspecting PH, but these may not …

Background Troponin elevation is common in hospitalized COVID-19 patients, but underlying
aetiologies are ill-defined. We used multi-parametric cardiovascular magnetic resonance (…

… Dr Howard has received speaker fees and honoraria from Actelion, GSK and Pfizer and
is on advisory boards for Actelion, Bayer, GSK, Pfizer and Novartis. Dr Lordan has received …

… Luc-Decoy-15a/16 therapeutic potential in a mouse limb ischemia (LI) model. LI increased
… in ischemic skeletal muscle and improved post-LI angiogenesis and perfusion recovery, with …

▪ Abstract The vasculature is one of the most important and complex organs in the mammalian
body. The first functional organ to form during embryonic development, the intricately …