[PDF][PDF] Genome-wide CRISPR screens reveal host factors critical for SARS-CoV-2 infection

…, SM Zhang, VR Graziano, CO Schmitz, JS Chen… - Cell, 2021 - cell.com
Identification of host genes essential for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection may reveal novel therapeutic targets and inform our understanding of …

PD-L1 promotes colorectal cancer stem cell expansion by activating HMGA1-dependent signaling pathways

…, JC Wei, P Yang, Q Wang, ZP Chen, WL Li, HC Chen… - Cancer letters, 2019 - Elsevier
PD-L1 is critical for tumor cell escape from immune surveillance by inhibiting T cell function
via the PD-1 receptor. Accumulating evidence demonstrates that anti-PD-L1 monoclonal …

Long noncoding RNA PVT1-214 promotes proliferation and invasion of colorectal cancer by stabilizing Lin28 and interacting with miR-128

F He, Z Song, H Chen, Z Chen, P Yang, W Li, Z Yang… - Oncogene, 2019 - nature.com
Long noncoding RNAs (lncRNAs) are implicated in human cancer, but their mechanisms of
action are largely unknown. In this study, we investigated lncRNA alterations that contribute …

A strong and tough polymer–carbon nanotube film for flexible and efficient electromagnetic interference shielding

LC Jia, MZ Li, DX Yan, CH Cui, HY Wu… - Journal of Materials …, 2017 - pubs.rsc.org
Carbon nanotube (CNT) films exhibit potential use in broad areas including energy-storage,
thermal management, and electromagnetic interference (EMI) shielding; however, their …

[HTML][HTML] Genome-wide CRISPR screen reveals host genes that regulate SARS-CoV-2 infection

…, SM Zhang, VR Graziano, CO Schmitz, JS Chen… - Biorxiv, 2020 - ncbi.nlm.nih.gov
Identification of host genes essential for SARS-CoV-2 infection may reveal novel therapeutic
targets and inform our understanding of COVID-19 pathogenesis. Here we performed a …

High strain tolerant EMI shielding using carbon nanotube network stabilized rubber composite

LC Jia, DX Yan, Y Yang, D Zhou, CH Cui… - Advanced Materials …, 2017 - Wiley Online Library
High density flexible electronic platforms experience strong electromagnetic interference (EMI)
influences from multiple devices and repeated deformation conditions such as stretching, …

Human WDR5 promotes breast cancer growth and metastasis via KMT2-independent translation regulation

WL Cai, JFY Chen, H Chen, E Wingrove, SJ Kurley… - Elife, 2022 - elifesciences.org
Metastatic breast cancer remains a major cause of cancer-related deaths in women, and
there are few effective therapies against this advanced disease. Emerging evidence suggests …

[HTML][HTML] Expression of EZH2 is associated with poor outcome in colorectal cancer

Z Chen, P Yang, W Li, F He, J Wei… - Oncology …, 2018 - spandidos-publications.com
Enhancer of zeste homolog 2 (EZH2), the critical component of polycomb group protein family,
has been demonstrated to be overexpressed in various types of human cancer, including …

Enhanced mechanical performance of segregated carbon nanotube/poly (lactic acid) composite for efficient electromagnetic interference shielding

L Xu, XP Zhang, CH Cui, PG Ren… - Industrial & …, 2019 - ACS Publications
Electrically conductive segregated networks were formed in carbon nanotube (CNT)/poly(lactic
acid) (PLA) composite, in which CNTs are selectively located in poly(l-lactide) (PLLA) …

[HTML][HTML] Gankyrin sustains PI3K/GSK-3β/β-catenin signal activation and promotes colorectal cancer aggressiveness and progression

F He, H Chen, P Yang, Q Wu, T Zhang, C Wang, J Wei… - Oncotarget, 2016 - ncbi.nlm.nih.gov
High levels of angiogenesis, metastasis and chemoresistance are major clinical features of
colorectal cancer (CRC), a lethal disease with a high incidence worldwide. Aberrant …