New epigallocatechin gallate (EGCG) nanocomplexes co-assembled with 3-mercapto-1-hexanol and β-lactoglobulin for improvement of antitumor activity

…, N Ravichandran, H Ying, C Yu, H Ying… - Journal of …, 2017 - ingentaconnect.com
(-)-Epigallocatechin-3-gallate (EGCG), as the major catechin in green tea, is a potent
antioxidant with numerous reported health benefits such as anti-proliferative and pro-apoptotic …

DPHL: a DIA pan-human protein mass spectrometry library for robust biomarker discovery

…, S Lou, Y Dai, C Xu, C Yu, H Ying… - Genomics …, 2020 - academic.oup.com
To address the increasing need for detecting and validating protein biomarkers in clinical
specimens, mass spectrometry (MS)-based targeted proteomic techniques, including the …

[HTML][HTML] Proteomic Dynamics of Breast Cancer Cell Lines Identifies Potential Therapeutic Protein Targets

…, J Fang, F Wu, H Xie, J Saez-Rodriguez, H Ying… - Molecular & Cellular …, 2023 - ASBMB
Abstract Treatment and relevant targets for breast cancer (BC) remain limited, especially for
triple-negative BC (TNBC). We identified 6091 proteins of 76 human BC cell lines using data-…

Sclareol ameliorates hyperglycemia‐induced renal injury through inhibiting the MAPK/NF‐κB signaling pathway

…, Q Shi, Y Zhang, J Ren, Y Wang, H Ying… - Phytotherapy …, 2022 - Wiley Online Library
… , Huazhong Ying, and Yi Wang contributed to the literature search and study design. Xue Han,
Yi Zhang, and Huazhong Ying … Xue Han and Huazhong Ying contributed to data collection …

(−)-Epigallocatechin gallate (EGCG)-nanoethosomes as a transdermal delivery system for docetaxel to treat implanted human melanoma cell tumors in mice

…, H Ying, C Yu, Z Fan, W Zhang, J Shi, H Ying… - International journal of …, 2016 - Elsevier
(−)-Epigallocatechin-3-O-gallate (EGCG), a versatile natural product in fresh tea leaves and
green tea, has been investigated as a preventative treatment for cancers and cardiovascular …

[HTML][HTML] USP33 promotes nonalcoholic fatty acid disease-associated fibrosis in gerbils via the c-myc signaling

X Ke, H Hu, Q Peng, H Ying, X Chu - Biochemical and Biophysical …, 2023 - Elsevier
Nonalcoholic fatty acid disease (NAFLD) is a common complication of obesity associated
with liver fibrosis. The underlying molecular mechanisms involved in the progression from …

[HTML][HTML] Circulating exo-miR-154-5p regulates vascular dementia through endothelial progenitor cell-mediated angiogenesis

…, Y Tu, J Wei, J Zhang, G Jiang, Q Shi, H Ying - Frontiers in Cellular …, 2022 - frontiersin.org
Background Vascular dementia (VaD) mainly results from cerebral vascular lesions and
tissue changes, which contribute to neurodegenerative processes. Effective therapeutic …

Macrophage SHP2 Deficiency Alleviates Diabetic Nephropathy via Suppression of MAPK/NF-ĸB-Dependent Inflammation

…, L Chen, Z Xu, L Zheng, C Zheng, Q Shi, H Ying… - Diabetes, 2024 - Am Diabetes Assoc
Increasing evidence implicates chronic inflammation as the main pathological cause of
diabetic nephropathy (DN). Exploration of key targets in the inflammatory pathway may provide …

Dectin1 contributes to hypertensive vascular injury by promoting macrophage infiltration through activating the Syk/NF-κB pathway

…, R Zheng, J Shao, Q Chen, G Liang, H Ying… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Vascular injury is an early manifestation leading to end-organ damage in hypertension
pathogenesis, which involves a macrophage-associated immune response. Dendritic cell-…

[HTML][HTML] Primary genetic investigation of a hyperlipidemia model: molecular characteristics and variants of the apolipoprotein E gene in Mongolian gerbil

Y Liu, J Wu, Q Shi, H Guo, H Ying, N Xu - Biomed Research …, 2014 - hindawi.com
The objective of this work was to establish a novel Mongolian gerbil (Meriones unguiculatus)
hyperlipidemia model and to investigate its susceptibility genetic basis. Two rodent (gerbil …