[HTML][HTML] Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization

…, L Hocqueloux, S Fafi-Kremer, T Prazuck, H Mouquet… - Nature, 2021 - nature.com
The SARS-CoV-2 B.1.617 lineage was identified in October 2020 in India 1 , 2 , 3 , 4 – 5 .
Since then, it has become dominant in some regions of India and in the UK, and has spread to …

Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies

H Mouquet, L Scharf, Z Euler, Y Liu… - Proceedings of the …, 2012 - National Acad Sciences
Broadly neutralizing HIV antibodies (bNAbs) can recognize carbohydrate-dependent epitopes
on gp120. In contrast to previously characterized glycan-dependent bNAbs that recognize …

[HTML][HTML] Considerable escape of SARS-CoV-2 Omicron to antibody neutralization

…, FA Rey, E Simon-Loriere, T Bruel, H Mouquet… - Nature, 2022 - nature.com
The SARS-CoV-2 Omicron variant was first identified in November 2021 in Botswana and
South Africa 1 , 2 – 3 . It has since spread to many countries and is expected to rapidly become …

A comparison of four serological assays for detecting anti–SARS-CoV-2 antibodies in human serum samples from different populations

…, B Hoen, T Bruel, M Eloit, H Mouquet… - Science translational …, 2020 - science.org
It is of paramount importance to evaluate the prevalence of both asymptomatic and symptomatic
cases of SARS-CoV-2 infection and their differing antibody response profiles. Here, we …

Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals

JF Scheid, H Mouquet, N Feldhahn, MS Seaman… - Nature, 2009 - nature.com
Antibodies to conserved epitopes on the human immunodeficiency virus (HIV) surface protein
gp140 can protect against infection in non-human primates, and some infected individuals …

[HTML][HTML] A single cycle of rituximab for the treatment of severe pemphigus

P Joly, H Mouquet, JC Roujeau… - … England Journal of …, 2007 - Mass Medical Soc
Background The combination of multiple cycles of rituximab and intravenous immune
globulins has been reported to be effective in patients with severe pemphigus. The aim of this …

Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation

H Mouquet, JF Scheid, MJ Zoller, M Krogsgaard… - Nature, 2010 - nature.com
During immune responses, antibodies are selected for their ability to bind to foreign antigens
with high affinity, in part by their ability to undergo homotypic bivalent binding. However, …

[HTML][HTML] Polyreactive antibodies in adaptive immune responses to viruses

H Mouquet, MC Nussenzweig - Cellular and Molecular Life Sciences, 2012 - Springer
B cells express immunoglobulins on their surface where they serve as antigen receptors.
When secreted as antibodies, the same molecules are key elements of the humoral immune …

[HTML][HTML] Sensitivity of infectious SARS-CoV-2 B. 1.1. 7 and B. 1.351 variants to neutralizing antibodies

…, E Simon-Lorière, S Fafi-Kremer, K Stefic, H Mouquet… - Nature medicine, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.1.7 and B.1.351 variants
were first identified in the United Kingdom and South Africa, respectively, and have since …

Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding

JF Scheid, H Mouquet, B Ueberheide, R Diskin, F Klein… - Science, 2011 - science.org
Passive transfer of broadly neutralizing HIV antibodies can prevent infection, which suggests
that vaccines that elicit such antibodies would be protective. Thus far, however, few broadly …