Gene expression profiling of 207 uniformly treated children with high-risk B-progenitor acute
lymphoblastic leukemia revealed 29 of 207 cases (14%) with markedly elevated expression …

To resolve the genetic heterogeneity within pediatric high-risk B-precursor acute lymphoblastic
leukemia (ALL), a clinically defined poor-risk group with few known recurring cytogenetic …

As controversy exists regarding the prognostic significance of genomic rearrangements of
CRLF2 in pediatric B-precursor acute lymphoblastic leukemia (ALL) classified as standard/…

To determine whether gene expression profiling could improve outcome prediction in children
with acute lymphoblastic leukemia (ALL) at high risk for relapse, we profiled pretreatment …

To determine whether gene expression profiling could improve risk classification and
outcome prediction in older acute myeloid leukemia (AML) patients, expression profiles were …

Early detection and accurate monitoring of chronic kidney disease (CKD) could improve care
and retard progression to end-stage renal disease. Here, using untargeted metabolomics …

Adenoid cystic carcinoma (ACC), the second most common malignancy of salivary glands, is
a rare tumor with a bleak prognosis for which therapeutic targets are unavailable. We used …

One recently identified subtype of pediatric B-precursor acute lymphoblastic leukemia (ALL)
has been termed BCR-ABL1–like or Ph-like because of similarity of the gene expression …

Outcome for children with childhood acute lymphoblastic leukemia (ALL) who relapse is poor.
To gain insight into the mechanisms of relapse, we analyzed gene-expression profiles in …

Gene expression profiling was performed on 97 cases of infant ALL from Children's Oncology
Group Trial P9407. Statistical modeling of an outcome predictor revealed 3 genes highly …