Hexanucleotide repeat expansions in the C9orf72 gene are a common genetic cause of
familial and sporadic amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). …

… Yin-Cheng Huang and Hung-Yu Shih contributed equally to … Yin-Cheng Huang and Hung-Yu
Shih contributed equally to … Yin-Cheng Huang and Hung-Yu Shih contributed equally to …

Vanishing white matter disease (VWM) is a severe leukodystrophy of the central nervous
system caused by mutations in subunits of the eukaryotic initiation factor 2B complex (eIF2B). …

The schizophrenia susceptibility gene, Rgs4, is one of the most intensively studied
regulators of G-protein signaling members, well known to be fundamental in regulating …

Glucose-6-phosphate dehydrogenase (G6PD) is a housekeeping enzyme involved in the
pentose phosphate shunt for producing nicotinamide adenine dinucleotide phosphate (NADPH…

Delta/notch-like epidermal growth factor (EGF)-related receptor (DNER) is a single-pass
transmembrane protein found to be a novel ligand in the Notch signaling pathway. Its function …

Glioblastomas are among the most fatal brain tumors; however, the molecular determinants
of their tumorigenic behavior are not adequately defined. In this study, we analyzed the role …

Neural crest progenitor cells, which give rise to many ectodermal and mesodermal derivatives,
must maintain a delicate balance of apoptosis and proliferation for their final tissue …

Background: Many molecules and signaling pathways involved in neural development play
a role in neurodegenerative diseases and brain tumor progression. Peroxisome proliferator‐…

Nuclear factor κB (NF-κB) is a eukaryotic transcription factor which responds to different
extracellular signals. It is involved in immune response, inflammation, and cell proliferation. …