Video-based pooled screening yields improved far-red genetically encoded voltage indicators

H Tian, HC Davis, JD Wong-Campos, P Park, LZ Fan… - Nature …, 2023 - nature.com
Video-based screening of pooled libraries is a powerful approach for directed evolution of
biosensors because it enables selection along multiple dimensions simultaneously from large …

Effect of deutetrabenazine on chorea among patients with Huntington disease: a randomized clinical trial

…, G Suter, J Jankovic, J Jimenez-Shahed, C Hunter… - Jama, 2016 - jamanetwork.com
Importance Deutetrabenazine is a novel molecule containing deuterium, which attenuates
CYP2D6 metabolism and increases active metabolite half-lives and may therefore lead to …

[HTML][HTML] Mapping the microscale origins of magnetic resonance image contrast with subcellular diamond magnetometry

HC Davis, P Ramesh, A Bhatnagar… - Nature …, 2018 - nature.com
Magnetic resonance imaging (MRI) is a widely used biomedical imaging modality that
derives much of its contrast from microscale magnetic field patterns in tissues. However, the …

[HTML][HTML] Non-invasive imaging using reporter genes altering cellular water permeability

A Mukherjee, D Wu, HC Davis, MG Shapiro - Nature communications, 2016 - nature.com
Non-invasive imaging of gene expression in live, optically opaque animals is important for
multiple applications, including monitoring of genetic circuits and tracking of cell-based …

Going deeper: biomolecular tools for acoustic and magnetic imaging and control of cellular function

DI Piraner, A Farhadi, HC Davis, D Wu, D Maresca… - Biochemistry, 2017 - ACS Publications
Most cellular phenomena of interest to mammalian biology occur within the context of living
tissues and organisms. However, today’s most advanced tools for observing and …

[PDF][PDF] Nanoscale heat transfer from magnetic nanoparticles and ferritin in an alternating magnetic field

HC Davis, S Kang, JH Lee, TH Shin, H Putterman… - Biophysical journal, 2020 - cell.com
Recent suggestions of nanoscale heat confinement on the surface of synthetic and biogenic
magnetic nanoparticles during heating by radio frequency-alternating magnetic fields have …

Safety of converting from tetrabenazine to deutetrabenazine for the treatment of chorea

…, E Furr-Stimming, M Gudesblatt, C Hunter… - JAMA …, 2017 - jamanetwork.com
… Dr Davis reported serving as a consultant for Auspex Pharmaceuticals. Dr Duker reported
receiving grants and nonfinancial support from HSG on behalf of Auspex Pharmaceuticals …

Biomolecular MRI reporters: Evolution of new mechanisms

A Mukherjee, HC Davis, P Ramesh, GJ Lu… - Progress in nuclear …, 2017 - Elsevier
Magnetic resonance imaging (MRI) is a powerful technique for observing the function of
specific cells and molecules inside living organisms. However, compared to optical microscopy, …

Isolation of the PufX Protein from Rhodobacter capsulatus and Rhodobacter sphaeroides:  Evidence for Its Interaction with the α-Polypeptide of the Core Light …

…, JT Beatty, PS Parkes-Loach, CN Hunter… - Biochemistry, 1998 - ACS Publications
Using mutant strains of Rhodobacter capsulatus and Rhodobacter sphaeroides in which the
pufX gene had been deleted, it was possible to identify by HPLC membrane protein …

All-optical electrophysiology with improved genetically encoded voltage indicators reveals interneuron network dynamics in vivo

H Tian, HC Davis, JD Wong-Campos, LZ Fan… - Biorxiv, 2021 - biorxiv.org
All-optical electrophysiology can be a powerful tool for studying neural dynamics in vivo, as
it offers the ability to image and perturb membrane voltage in multiple cells simultaneously. …