Video-based pooled screening yields improved far-red genetically encoded voltage indicators
Video-based screening of pooled libraries is a powerful approach for directed evolution of
biosensors because it enables selection along multiple dimensions simultaneously from large …
biosensors because it enables selection along multiple dimensions simultaneously from large …
Effect of deutetrabenazine on chorea among patients with Huntington disease: a randomized clinical trial
…, G Suter, J Jankovic, J Jimenez-Shahed, C Hunter… - Jama, 2016 - jamanetwork.com
Importance Deutetrabenazine is a novel molecule containing deuterium, which attenuates
CYP2D6 metabolism and increases active metabolite half-lives and may therefore lead to …
CYP2D6 metabolism and increases active metabolite half-lives and may therefore lead to …
[HTML][HTML] Mapping the microscale origins of magnetic resonance image contrast with subcellular diamond magnetometry
HC Davis, P Ramesh, A Bhatnagar… - Nature …, 2018 - nature.com
Magnetic resonance imaging (MRI) is a widely used biomedical imaging modality that
derives much of its contrast from microscale magnetic field patterns in tissues. However, the …
derives much of its contrast from microscale magnetic field patterns in tissues. However, the …
[HTML][HTML] Non-invasive imaging using reporter genes altering cellular water permeability
Non-invasive imaging of gene expression in live, optically opaque animals is important for
multiple applications, including monitoring of genetic circuits and tracking of cell-based …
multiple applications, including monitoring of genetic circuits and tracking of cell-based …
Going deeper: biomolecular tools for acoustic and magnetic imaging and control of cellular function
Most cellular phenomena of interest to mammalian biology occur within the context of living
tissues and organisms. However, today’s most advanced tools for observing and …
tissues and organisms. However, today’s most advanced tools for observing and …
[PDF][PDF] Nanoscale heat transfer from magnetic nanoparticles and ferritin in an alternating magnetic field
Recent suggestions of nanoscale heat confinement on the surface of synthetic and biogenic
magnetic nanoparticles during heating by radio frequency-alternating magnetic fields have …
magnetic nanoparticles during heating by radio frequency-alternating magnetic fields have …
Safety of converting from tetrabenazine to deutetrabenazine for the treatment of chorea
…, E Furr-Stimming, M Gudesblatt, C Hunter… - JAMA …, 2017 - jamanetwork.com
… Dr Davis reported serving as a consultant for Auspex Pharmaceuticals. Dr Duker reported
receiving grants and nonfinancial support from HSG on behalf of Auspex Pharmaceuticals …
receiving grants and nonfinancial support from HSG on behalf of Auspex Pharmaceuticals …
Biomolecular MRI reporters: Evolution of new mechanisms
Magnetic resonance imaging (MRI) is a powerful technique for observing the function of
specific cells and molecules inside living organisms. However, compared to optical microscopy, …
specific cells and molecules inside living organisms. However, compared to optical microscopy, …
Isolation of the PufX Protein from Rhodobacter capsulatus and Rhodobacter sphaeroides: Evidence for Its Interaction with the α-Polypeptide of the Core Light …
…, JT Beatty, PS Parkes-Loach, CN Hunter… - Biochemistry, 1998 - ACS Publications
Using mutant strains of Rhodobacter capsulatus and Rhodobacter sphaeroides in which the
pufX gene had been deleted, it was possible to identify by HPLC membrane protein …
pufX gene had been deleted, it was possible to identify by HPLC membrane protein …
All-optical electrophysiology with improved genetically encoded voltage indicators reveals interneuron network dynamics in vivo
All-optical electrophysiology can be a powerful tool for studying neural dynamics in vivo, as
it offers the ability to image and perturb membrane voltage in multiple cells simultaneously. …
it offers the ability to image and perturb membrane voltage in multiple cells simultaneously. …