Options and limitations in clinical investigation of bacterial biofilms

M Magana, C Sereti, A Ioannidis… - Clinical Microbiology …, 2018 - Am Soc Microbiol
Bacteria can form single- and multispecies biofilms exhibiting diverse features based upon
the microbial composition of their community and microenvironment. The study of bacterial …

Immune reconstitution inflammatory syndrome: the trouble with immunity when you had none

DL Barber, BB Andrade, I Sereti, A Sher - Nature reviews Microbiology, 2012 - nature.com
Some individuals who are infected with HIV rapidly deteriorate shortly after starting
antiretroviral therapy, despite effective viral suppression. This reaction, referred to as immune …

Immune restoration after antiretroviral therapy: the pitfalls of hasty or incomplete repairs

EMP Wilson, I Sereti - Immunological reviews, 2013 - Wiley Online Library
Antiretroviral therapy ( ART ) is a life‐saving intervention in human immunodeficiency virus (
HIV ) infection. Immune restoration after ART dramatically reduces the incidence and …

Plasma levels of soluble CD14 independently predict mortality in HIV infection

…, JM Brenchley, SG Deeks, I Sereti… - Journal of Infectious …, 2011 - academic.oup.com
Background . Chronic human immunodeficiency virus (HIV) infection is associated with intestinal
permeability and microbial translocation that contributes to systemic immune activation, …

The common γ-chain cytokines IL-2, IL-7, IL-15, and IL-21 induce the expression of programmed death-1 and its ligands

AL Kinter, EJ Godbout, JP McNally, I Sereti… - The Journal of …, 2008 - journals.aai.org
The programmed death (PD)-1 molecule and its ligands (PD-L1 and PD-L2), negative
regulatory members of the B7 family, play an important role in peripheral tolerance. Previous …

Higher levels of CRP, D-dimer, IL-6, and hyaluronic acid before initiation of antiretroviral therapy (ART) are associated with increased risk of AIDS or death

…, RM Novak, JD Neaton, I Sereti - Journal of Infectious …, 2011 - academic.oup.com
Background . Substantial morbidity occurs during the first year of antiretroviral therapy (ART)
in persons with advanced human immunodeficiency virus (HIV) disease despite HIV …

Analysis of nutrient flows in integrated intensive aquaculture systems

O Schneider, V Sereti, EH Eding, JAJ Verreth - Aquacultural engineering, 2005 - Elsevier
This paper analyses nutrient conversions, which are taking place in integrated intensive
aquaculture systems. In these systems fish is cultured next to other organisms, which are …

IL-7 administration drives T cell–cycle entry and expansion in HIV-1 infection

I Sereti, RM Dunham, J Spritzler, E Aga… - Blood, The Journal …, 2009 - ashpublications.org
Interleukin 7 (IL-7) is a common gamma chain receptor cytokine implicated in thymopoiesis
and in peripheral expansion and survival of T lymphocytes. The safety and activity of …

[HTML][HTML] Impact of multi-targeted antiretroviral treatment on gut T cell depletion and HIV reservoir seeding during acute HIV infection

J Ananworanich, A Schuetz, C Vandergeeten, I Sereti… - PloS one, 2012 - journals.plos.org
Background Limited knowledge exists on early HIV events that may inform preventive and
therapeutic strategies. This study aims to characterize the earliest immunologic and virologic …

Interleukin-7 promotes HIV persistence during antiretroviral therapy

…, S DaFonseca, MB Lawani, I Sereti… - Blood, The Journal …, 2013 - ashpublications.org
HIV persists in latently infected memory CD4 + T cells during antiretroviral therapy (ART).
When administered to HIV-infected subjects receiving suppressive ART, interleukin-7 (IL-7) …