User profiles for I. A. El-Shimy
 | Ismail Amr El-ShimyIntegrative Research Institute for Life Sciences (IRI), Humboldt-Universität zu Berlin Verified email at charite.de Cited by 125 |
[HTML][HTML] Neutrophil Elastase Inhibitors: A potential prophylactic treatment option for SARS-CoV-2-induced respiratory complications?
MMA Mohamed, IA El-Shimy, MA Hadi - Critical Care, 2020 - Springer
As the death toll from the COVID-19 pandemic caused by SARS-CoV-2 continues to mount
globally, scientists, healthcare agencies, and pharmaceutical companies are trying hard to …
globally, scientists, healthcare agencies, and pharmaceutical companies are trying hard to …
[HTML][HTML] Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium
…, C Giesecke-Thiel, S Schulze, IA El-Shimy… - Nature …, 2019 - nature.com
Oncogenic mutations in KRAS or BRAF are frequent in colorectal cancer and activate the
ERK kinase. Here, we find graded ERK phosphorylation correlating with cell differentiation in …
ERK kinase. Here, we find graded ERK phosphorylation correlating with cell differentiation in …
Targeting host cell proteases as a potential treatment strategy to limit the spread of SARS‐CoV‐2 in the respiratory tract
IA El‐Shimy, MMA Mohamed… - Pharmacology …, 2021 - Wiley Online Library
As the death toll of Coronavirus disease 19 (COVID‐19) continues to rise worldwide, it is
imperative to explore novel molecular mechanisms for targeting SARS‐CoV‐2. Rather than …
imperative to explore novel molecular mechanisms for targeting SARS‐CoV‐2. Rather than …
Minocycline attenuates Aβ oligomers-induced pro-inflammatory phenotype in primary microglia while enhancing Aβ fibrils phagocytosis
IA El-Shimy, OA Heikal, N Hamdi - Neuroscience letters, 2015 - Elsevier
Microglia, the brain innate immune cells, are activated in response to amyloid beta (Aβ)
resulting in neuroinflammation in AD brains. Recently, two phenotypes have been described for …
resulting in neuroinflammation in AD brains. Recently, two phenotypes have been described for …
Immunosuppression with Cyclosporine versus Tacrolimus shows distinctive nephrotoxicity profiles within renal compartments
…, S Popovic, C Dittmayer, DE Yilmaz, IA El-Shimy… - bioRxiv, 2023 - biorxiv.org
Calcineurin inhibitors (CNI) are the backbone for immunosuppression after solid organ
transplantation. Although successful in preventing kidney transplant rejection, their nephrotoxic …
transplantation. Although successful in preventing kidney transplant rejection, their nephrotoxic …
[HTML][HTML] Fabrication of doped ferrites and exploration of their structure and magnetic behavior
RE El-Shater, H El Shimy, SA Saafan, MA Darwish… - Materials …, 2023 - pubs.rsc.org
Manganese-doped MnxFe3−xO4 (x = 0.0, 0.2, 0.6, 0.8) spinel ferrites were produced via co-precipitation
using the ethanolamine. XRD results confirmed the formation of the spinel …
using the ethanolamine. XRD results confirmed the formation of the spinel …
[HTML][HTML] Reliability, availability and maintainability analysis for grid-connected solar photovoltaic systems
Recently, solar power generation is significantly contributed to growing renewable sources
of electricity all over the world. The reliability and availability improvement of solar …
of electricity all over the world. The reliability and availability improvement of solar …
Impact of subsystems on the overall system availability for the large scale grid-connected photovoltaic systems
A Sayed, M El-Shimy, M El-Metwally… - Reliability Engineering & …, 2020 - Elsevier
This paper demonstrates the impact of subsystem availability on a large scale grid-connected
photovoltaic (PV) systems’ performance. Subsystem denotes to the installation of some …
photovoltaic (PV) systems’ performance. Subsystem denotes to the installation of some …
[HTML][HTML] Analysis of a hybrid wind/photovoltaic energy system controlled by brain emotional learning-based intelligent controller
Recently, hybrid wind/PV microgrids have gained great attention all over the world. It has the
merits of being environmentally friendly, reliable, sustainable, and efficient compared to its …
merits of being environmentally friendly, reliable, sustainable, and efficient compared to its …
Developing a new model for predicting global solar radiation on a horizontal surface located in Southwest Region of Algeria
…, YA Abdel-Hadi, M El-Shimy… - NRIAG Journal of …, 2020 - Taylor & Francis
… In: EL-Shimy M, editor. Economics of variable renewable sources for electric power
production:519-528. Lambert Academic Publishing / Omniscriptum Gmbh & Company Kg., Germany. …
production:519-528. Lambert Academic Publishing / Omniscriptum Gmbh & Company Kg., Germany. …