Carlos Chagas discovered American trypanosomiasis, also named Chagas disease (CD) in
his honor, just over a century ago. He described the clinical aspects of the disease, …

Chagas disease (CD), a neglected tropical disease caused by the protozoan Trypanosoma
cruzi, affects around six million individuals in Latin America. Currently, CD occurs worldwide, …

Ficolins are pattern-recognition proteins involved in innate immunity, which upon binding to
their specific pathogen-associated molecular patterns on the microbial surfaces trigger the …

Background Polymorphisms of the mannose-binding lectin gene (MBL2) affect the concentration
and functional efficiency of the protein. We recently used haplotype-specific sequencing …

… Messias Reason et al. lie in the fact that all our patients have aortic valvular lesion while
those of Messias Reason … Brazilian ethnicity in contrast to those of Messias Reason et al. (26), …

Celiac disease (CD), despite its high morbidity, is an often-underdiagnosed autoimmune
enteropathy. Using a modified version of the Brazilian questionnaire of the 2013 National …

BACKGROUND/AIMS: Lupus nephritis (LN) is one of the most serious manifestations of
SLE occurring in 66–90% of these patients. The complement system is part of the innate …

Piper amalago L., Piperaceae, popularly known as jaborandi-manso, is a shrub that spans
a height of 2–7 m. It can be found in the regions of Southern America downward up to the …

… Iara Jose de Messias-Reason … Iara Jose de Messias-Reason … De Messias-Reason IJ,
Boldt ABW, Moraes Braga AC, Von Rosen Seeling Stahlke E, Dornelles L, Pereira-Ferrari L, et al. …

Down syndrome (DS) is the most frequent cause of intellectual disability worldwide. DS
individuals present abnormalities in the immune system that include high susceptibility to …