Annexins and endocytosis

CE Futter, IJ White - Traffic, 2007 - Wiley Online Library
Annexins are calcium‐ and phospholipid‐binding proteins that have been proposed to have
multiple roles in membrane traffic. Historically, this has been based on the in vitro properties …

σB Modulates Virulence Determinant Expression and Stress Resistance: Characterization of a Functional rsbU Strain Derived from Staphylococcus aureus 8325-4

MJ Horsburgh, JL Aish, IJ White, L Shaw… - Journal of …, 2002 - Am Soc Microbiol
The accessory sigma factor σ B controls a general stress response that is thought to be
important for Staphylococcus aureus survival and may contribute to virulence. The strain of …

[PDF][PDF] A central role for the ERK-signaling pathway in controlling Schwann cell plasticity and peripheral nerve regeneration in vivo

…, LH Rosenberg, MJ Collins, MC Harrisingh, IJ White… - Neuron, 2012 - cell.com
… We collected blood from adult rats, purified the white blood cell fraction and found that CM
from tamoxifentreated cells attracted significantly more monocytes, T cells, and granulocytes …

EGF stimulates annexin 1‐dependent inward vesiculation in a multivesicular endosome subpopulation

IJ White, LM Bailey, MR Aghakhani, SE Moss… - The EMBO …, 2006 - embopress.org
Here we show that EGF and EGF receptor (EGFR) are trafficked through a subpopulation of
multivesicular endosomes/bodies (MVBs) that are distinct from morphologically identical …

Down-regulation of epidermal growth factor receptor signalling within multivesicular bodies

ER Eden, IJ White, CE Futter - Biochemical Society Transactions, 2009 - portlandpress.com
Activated EGFR (epidermal growth factor receptor) undergoes ESCRT (endosomal sorting
complex required for transport)-mediated sorting on to the intraluminal vesicles of MVBs (…

Membrane contacts between endosomes and ER provide sites for PTP1B–epidermal growth factor receptor interaction

ER Eden, IJ White, A Tsapara, CE Futter - Nature cell biology, 2010 - nature.com
The epidermal growth factor receptor (EGFR) is a critical determinator of cell fate. Signalling
from this receptor tyrosine kinase is spatially regulated by progression through the endocytic …

Pathophysiology of Dyt1-Tor1a dystonia in mice is mediated by spinal neural circuit dysfunction

…, F Nascimento, MG Özyurt, IJ White… - Science translational …, 2023 - science.org
Dystonia, a neurological disorder defined by abnormal postures and disorganized movements,
is considered to be a neural circuit disorder with dysfunction arising within and between …

Actomyosin II contractility expels von Willebrand factor from Weibel–Palade bodies during exocytosis

TD Nightingale, IJ White, EL Doyle, M Turmaine… - Journal of cell …, 2011 - rupress.org
The study of actin in regulated exocytosis has a long history with many different results in
numerous systems. A major limitation on identifying precise mechanisms has been the paucity …

Retinaldehyde dehydrogenase 1 regulates a thermogenic program in white adipose tissue

FW Kiefer, C Vernochet, P O'brien, S Spoerl… - Nature medicine, 2012 - nature.com
… role for retinoid metabolism in white versus brown fat is … is expressed predominately in
white adipose tissue (WAT), … and protein levels in white adipocytes by selectively activating …

[PDF][PDF] Characterization of the structure and control of the blood-nerve barrier identifies avenues for therapeutic delivery

L Malong, I Napoli, G Casal, IJ White, S Stierli… - Developmental cell, 2023 - cell.com
The blood barriers of the nervous system protect neural environments but can hinder
therapeutic accessibility. The blood-brain barrier (BBB) is well characterized, consisting of …