Nociceptor sensory neurons are specialized to detect potentially damaging stimuli,
protecting the organism by initiating the sensation of pain and eliciting defensive behaviours. …

Type 2 innate lymphoid cells (ILC2s) both contribute to mucosal homeostasis and initiate
pathologic inflammation in allergic asthma. However, the signals that direct ILC2s to promote …

Lung-innervating nociceptor sensory neurons detect noxious or harmful stimuli and consequently
protect organisms by mediating coughing, pain, and bronchoconstriction. However, the …

Nociceptor sensory neurons protect organisms from danger by eliciting pain and driving
avoidance. Pain also accompanies many types of inflammation and injury. It is increasingly …

The peripheral nervous and immune systems are traditionally thought of as serving separate
functions. The line between them is, however, becoming increasingly blurred by new …

Pain is a hallmark of tissue injury, inflammatory diseases, pathogen invasion and neuropathy.
It is mediated by nociceptor sensory neurons that innervate the skin, joints, bones, …

Microglia are resident immune cells of the CNS that are activated by infection, neuronal
injury, and inflammation. Here, we utilize flow cytometry and deep RNA sequencing of acutely …

DOI: 10.1002/adma. 201500762 in the nervous system are able to differentiate into neurons
and glial cells and are a potential cellular source for neural regeneration. The fates of NSCs …

Amyotrophic Lateral Sclerosis (ALS) is an adult-onset, progressive, motor neuron degenerative
disease, in which the role of inflammation is not well established. Innate and adaptive …

Several of the endothelial cell polypeptide mitogens that have been described probably play
a role in blood vessel homeostasis. Two overlapping complementary DNA clones encoding …