User profiles for I. M. Tolic
Iva M. TolićRuđer Bošković Institute Verified email at irb.hr Cited by 8537 |
Self-organization and forces in the mitotic spindle
… We thank the members of the Tolić and Pavin groups and other collaborators for their
contributions to the work discussed in this review; Juraj Simunić and Lejla Ferhatović Hamzić for …
contributions to the work discussed in this review; Juraj Simunić and Lejla Ferhatović Hamzić for …
[HTML][HTML] Mitotic spindle: kinetochore fibers hold on tight to interpolar bundles
IM Tolić - European Biophysics Journal, 2018 - Springer
… 2016a; Pavin and Tolic-Norrelykke 2014), may help the microtubules extending from the
two poles to find each other much faster than in the case without rotation (Fig. 6b). A recent …
two poles to find each other much faster than in the case without rotation (Fig. 6b). A recent …
[PDF][PDF] Mechanobiology of the mitotic spindle
… This movement together with a constant spindle length during metaphase implies that the
kinetochore microtubules simultaneously polymerize at the kinetochore and depolymerize at …
kinetochore microtubules simultaneously polymerize at the kinetochore and depolymerize at …
Modeling the insulin–glucose feedback system: the significance of pulsatile insulin secretion
IM Tolić, E Mosekilde, J Sturis - Journal of theoretical biology, 2000 - Elsevier
A mathematical model of the insulin–glucose feedback regulation in man is used to examine
the effects of an oscillatory supply of insulin compared to a constant supply at the same …
the effects of an oscillatory supply of insulin compared to a constant supply at the same …
[HTML][HTML] Nuclear chromosome locations dictate segregation error frequencies
… We thank members of the Kops, Lens and Tolić laboratories for discussions and comments
on the manuscript. Figure 3d and Extended Data Figs. 6f and 9 were created with Biorender.…
on the manuscript. Figure 3d and Extended Data Figs. 6f and 9 were created with Biorender.…
[HTML][HTML] Overlap microtubules link sister k-fibres and balance the forces on bi-oriented kinetochores
During metaphase, forces on kinetochores are exerted by k-fibres, bundles of microtubules
that end at the kinetochore. Interestingly, non-kinetochore microtubules have been observed …
that end at the kinetochore. Interestingly, non-kinetochore microtubules have been observed …
[PDF][PDF] Microtubule sliding within the bridging fiber pushes kinetochore fibers apart to segregate chromosomes
During cell division, mitotic spindle microtubules segregate chromosomes by exerting
forces on kinetochores. What forces drive chromosome segregation in anaphase remains a …
forces on kinetochores. What forces drive chromosome segregation in anaphase remains a …
PRC 1‐labeled microtubule bundles and kinetochore pairs show one‐to‐one association in metaphase
In the mitotic spindle, kinetochore microtubules form k‐fibers, whereas overlap or interpolar
microtubules form antiparallel arrays containing the cross‐linker protein regulator of …
microtubules form antiparallel arrays containing the cross‐linker protein regulator of …
[HTML][HTML] Microtubule-sliding modules based on kinesins EG5 and PRC1-dependent KIF4A drive human spindle elongation
K Vukušić, I Ponjavić, R Buđa, P Risteski, IM Tolić - Developmental Cell, 2021 - Elsevier
Proper chromosome segregation into two future daughter cells requires the mitotic spindle
to elongate in anaphase. However, although some candidate proteins are implicated in this …
to elongate in anaphase. However, although some candidate proteins are implicated in this …
Optogenetic control of PRC1 reveals its role in chromosome alignment on the spindle by overlap length-dependent forces
During metaphase, chromosome position at the spindle equator is regulated by the forces
exerted by kinetochore microtubules and polar ejection forces. However, the role of forces …
exerted by kinetochore microtubules and polar ejection forces. However, the role of forces …