User profiles for I. R. Efimov

Igor R. Efimov

Professor of Biomedical Engineering, Professor of Medicine, Northwestern University …
Verified email at northwestern.edu
Cited by 19635

Optical imaging of the heart

IR Efimov, VP Nikolski, G Salama - Circulation research, 2004 - Am Heart Assoc
Optical techniques have revolutionized the investigation of cardiac cellular physiology and
advanced our understanding of basic mechanisms of electrical activity, calcium homeostasis, …

Processing and analysis of cardiac optical mapping data obtained with potentiometric dyes

…, MS Sulkin, RM Arthur, IR Efimov - American Journal of …, 2012 - journals.physiology.org
Optical mapping has become an increasingly important tool to study cardiac electrophysiology
in the past 20 years. Multiple methods are used to process and analyze cardiac optical …

Connexins in the sinoatrial and atrioventricular nodes

…, R Billeter, M Lei, H Zhang, IR Efimov… - Cardiovascular gap …, 2006 - karger.com
The sinoatrial node (SAN) and the atrioventricular node (AVN) are specialized tissues in the
heart: the SAN is specialized for pacemaking (it is the pacemaker of the heart), whereas the …

[HTML][HTML] 3D multifunctional integumentary membranes for spatiotemporal cardiac measurements and stimulation across the entire epicardium

…, JW Jeong, GT Kim, Y Huang, IR Efimov… - Nature …, 2014 - nature.com
Means for high-density multiparametric physiological mapping and stimulation are critically
important in both basic and clinical cardiology. Current conformal electronic systems are …

Fully implantable and bioresorbable cardiac pacemakers without leads or batteries

…, GD Trachiotis, BP Knight, RK Arora, IR Efimov… - Nature …, 2021 - nature.com
Temporary cardiac pacemakers used in periods of need during surgical recovery involve
percutaneous leads and externalized hardware that carry risks of infection, constrain patient …

Mechanisms of cardiac and renal dysfunction in patients dying of sepsis

…, RE Fagley, B Sato, S Jarman, IR Efimov… - American journal of …, 2013 - atsjournals.org
Rationale: The mechanistic basis for cardiac and renal dysfunction in sepsis is unknown. In
particular, the degree and type of cell death is undefined. Objectives: To evaluate the degree …

Application of blebbistatin as an excitation–contraction uncoupler for electrophysiologic study of rat and rabbit hearts

…, EP Anyukhovsky, MR Rosen, CW Balke, IR Efimov - Heart rhythm, 2007 - Elsevier
BACKGROUND: Application of fluorescence imaging of cardiac electrical activity is limited
by motion artifacts and/or side effects of currently available pharmacologic excitation–…

Transmural dispersion of repolarization in failing and nonfailing human ventricle

…, RB Schuessler, N Moazami, IR Efimov - Circulation …, 2010 - Am Heart Assoc
Rationale: Transmural dispersion of repolarization has been shown to play a role in the
genesis of ventricular tachycardia and fibrillation in different animal models of heart failure (HF). …

Catheter-integrated soft multilayer electronic arrays for multiplexed sensing and actuation during cardiac surgery

…, G Yang, R Ghaffari, Y Huang, IR Efimov… - Nature biomedical …, 2020 - nature.com
… Synchronized temperature recordings from an infrared camera and the sensor array under
irradiation by ultraviolet (UV) laser to create a distribution of heating by optical absorption …

Photocurable bioresorbable adhesives as functional interfaces between flexible bioelectronic devices and soft biological tissues

…, JM Torkelson, Y Huang, Y Kozorovitskiy, IR Efimov… - Nature materials, 2021 - nature.com
Flexible electronic/optoelectronic systems that can intimately integrate onto the surfaces of
vital organ systems have the potential to offer revolutionary diagnostic and therapeutic …