User profiles for I. V. Manzanera Esteve

Isaac Manzanera Esteve

Imaging Research Scientist
Verified email at vumc.org
Cited by 182

Efficient Synthesis of Molecular Precursors for Para‐Hydrogen‐Induced Polarization of Ethyl Acetate‐1‐13C and Beyond

…, AM Coffey, IV Manzanera Esteve… - Angewandte …, 2016 - Wiley Online Library
A scalable and versatile methodology for production of vinylated carboxylic compounds with
13 C isotopic label in C1 position is described. It allowed synthesis of vinyl acetate‐1‐ 13 C, …

Parahydrogen-Induced Polarization of 1-13C-Acetates and 1-13C-Pyruvates Using Sidearm Hydrogenation of Vinyl, Allyl, and Propargyl Esters

…, RV Shchepin, IV Manzanera Esteve… - The Journal of …, 2019 - ACS Publications
… Thus, HP magnetic resonance spectroscopic imaging quantification of the lactate-to-pyruvate
ratio can be used for cancer diagnosis using the intravenous injection of HP pyruvate, …

Initial findings in traumatic peripheral nerve injury and repair with diffusion tensor imaging

…, AC Pollins, IV Manzanera Esteve… - Annals of Clinical …, 2021 - Wiley Online Library
Objective Management of peripheral nerve injuries requires physicians to rely on qualitative
measures from patient history, electromyography, and physical exam. Determining a …

[HTML][HTML] Probabilistic assessment of nerve regeneration with diffusion MRI in rat models of peripheral nerve trauma

IV Manzanera Esteve, AF Farinas, AC Pollins… - Scientific Reports, 2019 - nature.com
Nerve regeneration after injury must occur in a timely fashion to restore function. Unfortunately,
current methods (eg, electrophysiology) provide limited information following trauma, …

[HTML][HTML] Low-salt diet reduces anti-CTLA4 mediated systemic immune-related adverse events while retaining therapeutic efficacy against breast cancer

D Khandekar, DO Dahunsi, IV Manzanera Esteve… - Biology, 2022 - mdpi.com
… of excessive pain, stress, injury or distress): (i) if the animal is impeded in its ability to
ambulate; (ii) cannot obtain food or water; (iii) has 20% weight loss from starting body weight; (iv) …

Longitudinal traumatic peripheral nerve injury recovery: quantitative description, classification and prediction

IV Manzanera Esteve, AC Pollins… - Regenerative …, 2023 - Future Medicine
Aim: Repair of peripheral nerves is recommended following transection. Systematic evaluation
of longitudinal recovery in injury models is needed to improve patient management. …

Diffusion tensor tractrography visualizes partial nerve laceration severity as early as 1 week after surgical repair in a rat model ex vivo

AF Farinas, IV Manzanera Esteve, AC Pollins… - Military …, 2020 - academic.oup.com
Background: Previous studies in our laboratory have demonstrated that a magnetic resonance
imaging method called diffusion tensor imaging (DTI) can differentiate between crush and …

Effect of direct transportation to thrombectomy-capable center vs local stroke center on neurological outcomes in patients with suspected large-vessel occlusion stroke …

…, D Cocho, F Purroy, J Serena, LSR Manzanera… - Jama, 2022 - jamanetwork.com
… There were 11 secondary outcomes, including rate of intravenous tissue plasminogen
activator administration and thrombectomy in the target population and 90-day mortality in the …

[HTML][HTML] Model-based parcellation of diffusion MRI of injured spinal cord predicts hand use impairment and recovery in squirrel monkeys

IVM Esteve, F Wang, JL Reed, HX Qi, W Thayer… - Behavioural brain …, 2024 - Elsevier
Manzanera Esteve a b , Feng Wang b c , Jamie L. Reed b c , Hui Xin Qi e , Wesley Thayer a
, … 4A); and (iv) it identifies time-varying expansion and contraction of tissues associated with …

Correction for T1 effects on MRI estimation of muscle sodium levels

P Wang, M Esteve IV, C Nockowski… - Proc. of ISMRM …, 2015 - archive.ismrm.org
The effects of T1 on estimates of sodium content in human muscle have been evaluated.
Our data confirm that sodium levels estimated by comparing MRI signals to calibration …