Calcium-binding proteins: selective markers of nerve cells

C Andressen, I Blümcke, MR Celio - Cell and tissue research, 1993 - Springer
A characteristic of nerve cells is their ability to propagate an action potential and to communicate
through specialized contact zones, called synapses. Synapses have received much …

Infections, inflammation and epilepsy

…, RS Fujinami, HS White, PM Preux, I Blümcke… - Acta …, 2016 - Springer
Epilepsy is the tendency to have unprovoked epileptic seizures. Anything causing structural
or functional derangement of brain physiology may lead to seizures, and different conditions …

Perineuronal nets—a specialized form of extracellular matrix in the adult nervous system

MR Celio, I Blumcke - Brain Research Reviews, 1994 - Elsevier
One century ago, Camillo Golgi described ‘perineuronal nets’ enwrapping the cell bodies and
proximal dendrites of certain neurons in the adult mammalian central nervous system and …

The clinicopathologic spectrum of focal cortical dysplasias: A consensus classification proposed by an ad hoc task force of the ILAE Diagnostic Methods Commission 1

I Blümcke, M Thom, E Aronica, DD Armstrong… - 2011 - Wiley Online Library
Purpose: Focal cortical dysplasias (FCD) are localized regions of malformed cerebral cortex
and are very frequently associated with epilepsy in both children and adults. A broad …

DNA methylation-based classification of central nervous system tumours

…, P Wesseling, M Weller, VP Collins, I Blümcke… - Nature, 2018 - nature.com
Accurate pathological diagnosis is crucial for optimal management of patients with cancer.
For the approximately 100 known tumour types of the central nervous system, standardization …

International consensus classification of hippocampal sclerosis in temporal lobe epilepsy: a Task Force report from the ILAE Commission on Diagnostic Methods

I Blümcke, M Thom, E Aronica, DD Armstrong… - …, 2013 - Wiley Online Library
Hippocampal sclerosis ( HS ) is the most frequent histopathology encountered in patients
with drug‐resistant temporal lobe epilepsy ( TLE ). Over the past decades, various attempts …

[HTML][HTML] Histopathological findings in brain tissue obtained during epilepsy surgery

I Blumcke, R Spreafico, G Haaker… - … England Journal of …, 2017 - Mass Medical Soc
Background Detailed neuropathological information on the structural brain lesions underlying
seizures is valuable for understanding drug-resistant focal epilepsy. Methods We report …

NeuN: a useful neuronal marker for diagnostic histopathology.

…, T Pietsch, OD Wiestler, I Blümcke - … of Histochemistry & …, 1996 - journals.sagepub.com
The monoclonal antibody A60 specifically recognizes the DNA-binding, neuron-specific
protein NeuN, which is present in most neuronal cell types of vertebrates. In this study we …

The spectrum of long‐term epilepsy–associated tumors: long‐term seizure and tumor outcome and neurosurgical aspects

C Luyken, I Blümcke, R Fimmers, H Urbach… - …, 2003 - Wiley Online Library
Purpose: To describe the histologic spectrum and clinical characteristics of patients with
neuroepithelial tumors and drug‐resistant epilepsy and to analyze clinical data and treatment …

Immunopathology of autoantibody-associated encephalitides: clues for pathogenesis

CG Bien, A Vincent, MH Barnett, AJ Becker, I Blümcke… - Brain, 2012 - academic.oup.com
Classical paraneoplastic encephalitis syndromes with ‘onconeural’ antibodies directed to
intracellular antigens, and the recently described paraneoplastic or non-paraneoplastic …