Clostridium difficile is a Gram-positive spore-forming anaerobe and a major cause of
antibiotic-associated diarrhoea. Disruption of the commensal microbiota, such as through treatment …

Members of the Mycobacterium tuberculosis complex (MTBC) show distinct host adaptations,
preferences and phenotypes despite being >99% identical at the nucleic acid level. …

Tuberculosis has severe impacts on both humans and animals. Understanding the genetic
basis of survival of both Mycobacterium tuberculosis , the human-adapted species, and …

In this work, we compared the profile of proteins secreted by planktonic and biofilm cultures
of Pseudomonas aeruginosa using two-dimensional difference gel electrophoresis (2D-DiGE…

Glycoengineering of recombinant glycans and glycoconjugates is a rapidly evolving field.
However, the production and exploitation of glycans has lagged behind that of proteins and …

Background Actinobacillus pleuropneumoniae is the causative agent of porcine pleuropneumonia
and represents a major burden to the livestock industry. Virulence can largely be …

In Escherichia coli , citrate-mediated iron transport is a key nonheme pathway for the
acquisition of iron. Binding of ferric citrate to the outer membrane protein FecA induces a signal …

Conjugate vaccines produced either by chemical or biologically conjugation have been
demonstrated to be safe and efficacious in protection against several deadly bacterial diseases. …

Strep A is a human-exclusive bacterial pathogen killing annually more than 500,000 patients,
and no current licensed vaccine exists. Strep A bacteria are highly diverse, but all produce …

The opportunistic pathogen Pseudomonas aeruginosa commonly causes chronic and
ultimately deadly lung infections in individuals with the genetic disease cystic fibrosis (CF). P. …