The accessory sigma factor σ B controls a general stress response that is thought to be
important for Staphylococcus aureus survival and may contribute to virulence. The strain of …

Following damage to peripheral nerves, a remarkable process of clearance and regeneration
takes place. Axons downstream of the injury degenerate, while the nerve is remodeled to …

Here we show that EGF and EGF receptor (EGFR) are trafficked through a subpopulation of
multivesicular endosomes/bodies (MVBs) that are distinct from morphologically identical …

The epidermal growth factor receptor (EGFR) is a critical determinator of cell fate. Signalling
from this receptor tyrosine kinase is spatially regulated by progression through the endocytic …

Annexins are calcium‐ and phospholipid‐binding proteins that have been proposed to have
multiple roles in membrane traffic. Historically, this has been based on the in vitro properties …

The study of actin in regulated exocytosis has a long history with many different results in
numerous systems. A major limitation on identifying precise mechanisms has been the paucity …

InterFeron Inducible TransMembrane proteins 1–3 (IFITM1, IFITM2 and IFITM3) are a family
of proteins capable of inhibiting the cellular entry of numerous human and animal viruses. …

Peripheral nerves are highly regenerative, in contrast to the poor regenerative capabilities
of the central nervous system (CNS). Here, we show that adult peripheral nerve is a more …

N-cadherin is a homophilic adhesion protein that remains expressed at mature excitatory
synapses beyond its developmental role in synapse formation. We investigated the trans-…

Activated EGFR (epidermal growth factor receptor) undergoes ESCRT (endosomal sorting
complex required for transport)-mediated sorting on to the intraluminal vesicles of MVBs (…