High fidelity during protein synthesis is accomplished by aminoacyl-tRNA synthetases (aaRSs).
These enzymes ligate an amino acid to a cognate tRNA and have proofreading and …

Chromosomally-encoded toxin-antitoxin complexes are ubiquitous in bacteria and regulate
growth through the release of the toxin component typically in a stress-dependent manner. …

Purpose To improve the stability of pectin-oligochitosan hydrogel microcapsules under
physiological conditions. Methods Two different approaches were examined: change of the cross-…

Regulation of ubiquitous bacterial type II toxin-antitoxin (TA) gene pairs occurs via a negative
feedback loop whereby their expression is typically responsive to changing levels of toxins …

Bacteria utilize a vast array of systems to control their growth and metabolism. Tightly regulating
the process of DNA replication, transcription, and/or translation significantly alters the …

Antibiotic resistance is the most prominent threat facing modern medicine and is unlikely to
be resolved by novel antibiotics or reduction of improper antibiotic use. New strategies to …

Figure S1. Electron density maps of YoeB bound to the ribosome.(A) 2Fo-Fc electron
density maps (contoured at 1σ) for the YoeB dimer (green and pink) is shown for the 3.7-Å x-ray …

Bacterial toxin‐antitoxin systems are abundant genes that modulate a beneficial phenotypic
switch to shift cells' focus towards survival in times of stress, including antibiotic exposure. …

Advances in regenerative medicine and in modern biomedical therapies are fast evolving
and set goals causing an upheaval in the field of materials science. This review discusses …