Pre-marked chromatin and transcription factor co-binding shape the pioneering activity of Foxa2

…, P Smialowski, S Groh, IM Evenroed… - Nucleic Acids …, 2019 - academic.oup.com
Pioneer transcription factors (PTF) can recognize their binding sites on nucleosomal DNA
and trigger chromatin opening for recruitment of other non-pioneer transcription factors. …

[HTML][HTML] Transcriptomics of the vaccine immune response: priming with adjuvant modulates recall innate responses after boosting

…, F Fiorino, GD Gilfillan, IM Evenroed… - Frontiers in …, 2018 - frontiersin.org
Transcriptomic profiling of the immune response induced by vaccine adjuvants is of critical
importance for the rational design of vaccination strategies. In this study, transcriptomics was …

[HTML][HTML] Rheumatoid Arthritis Patients, Both Newly Diagnosed and Methotrexate Treated, Show More DNA Methylation Differences in CD4+ Memory Than in CD4+ …

…, S Lillegraven, AB Aga, IM Evenrød… - Frontiers in …, 2020 - frontiersin.org
Background: Differences in DNA methylation have been reported in B and T lymphocyte
populations, including CD4 + T cells, isolated from rheumatoid arthritis (RA) patients when …

[HTML][HTML] Methotrexate treatment of newly diagnosed RA patients is associated with DNA methylation differences at genes relevant for disease pathogenesis and …

…, MD Mjaavatten, ES Norli, IM Evenrød… - Frontiers in …, 2021 - frontiersin.org
Background Methotrexate (MTX) is the first line treatment of rheumatoid arthritis (RA), and
methylation changes in bulk T cells have been reported after treatment with MTX. We have …

Ephrin-B3 binds to a sulfated cell-surface receptor

…, L Zernichow, KE Fjelland, IM Evenroed… - Biochemical …, 2011 - portlandpress.com
The ephrins are a family of proteins known to bind the Eph (erythropoietin-producing
hepatocellular) receptor tyrosine kinase family. In the present paper, we provide data showing that …

[CITATION][C] Discovery of enzymes and accessory proteins for biomass conversion using the genome and proteome of Streptomyces coelicolor

IM Evenrød - 2008 - agris.fao.org
Discovery of enzymes and accessory proteins for biomass conversion using the genome
and proteome of Streptomyces coelicolor Food and Agriculture Organization of the United …

ADITEC: joining forces for next-generation vaccines

R Rappuoli, D Medaglini - Science translational medicine, 2012 - science.org
Scientists sit poised at a singular moment in the history of vaccine research. Genomics and
systems biology have fueled advances in our understanding of human immunology. …

Activation of EphA receptors on CD4+CD45RO+ memory cells stimulates migration

HL Holen, K Nustad, HC Aasheim - Journal of leukocyte biology, 2010 - academic.oup.com
The expression differences of EphA4 receptor on subpopulations of CD4 + T cells is related
to the migration potential after ephrin-A1 stimulation. We have demonstrated previously that …

Ephrin-B3 binds both cell-associated and secreted proteoglycans

K Prydz, TS Halstensen, HL Holen… - … and biophysical research …, 2018 - Elsevier
… The culture media were loaded onto DEAE-sepharose columns, washed with 2 vol 0.3 M
NaCl, and eluted with 1 ml 1 M NaCl. As in the metabolic labelling experiment, most PGs have …

[HTML][HTML] Downregulation of TFPI in breast cancer cells induces tyrosine phosphorylation signaling and increases metastatic growth by stimulating cell motility

…, HC Aasheim, M Tinholt, L Zernichow, M Sletten… - BMC cancer, 2011 - Springer
Background Increased hemostatic activity is common in many cancer types and often causes
additional complications and even death. Circumstantial evidence suggests that tissue …