Universal computing by DNA origami robots in a living animal

…, D Levner, S Ittah, A Abu-Horowitz, I Bachelet - Nature …, 2014 - nature.com
Biological systems are collections of discrete molecular objects that move around and
collide with each other. Cells carry out elaborate processes by precisely controlling these …

Mast cells: not only in allergy

I Bachelet, F Levi-Schaffer… - … and Allergy Clinics, 2006 - immunology.theclinics.com
Mast cells are known to be the central effector cells in the early phase and important in the
late phase of IgE-mediated allergic inflammatory reactions [1]. Mast cells can be activated to …

Diversity and functional landscapes in the microbiota of animals in the wild

…, D Futorian, D Gal, S Leviatan, D Zeevi, I Bachelet… - Science, 2021 - science.org
Animals in the wild are able to subsist on pathogen-infected and poisonous food and show
immunity to various diseases. These may be due to their microbiota, yet we have a poor …

A logic-gated nanorobot for targeted transport of molecular payloads

SM Douglas, I Bachelet, GM Church - Science, 2012 - science.org
We describe an autonomous DNA nanorobot capable of transporting molecular payloads to
cells, sensing cell surface inputs for conditional, triggered activation, and reconfiguring its …

High-resolution antibody dynamics of vaccine-induced immune responses

…, R Chari, JH Lee, I Bachelet… - Proceedings of the …, 2014 - National Acad Sciences
The adaptive immune system confers protection by generating a diverse repertoire of antibody
receptors that are rapidly expanded and contracted in response to specific targets. Next-…

The inhibitory receptor IRp60 (CD300a) suppresses the effects of IL-5, GM-CSF, and eotaxin on human peripheral blood eosinophils

A Munitz, I Bachelet, R Eliashar, A Moretta, L Moretta… - Blood, 2006 - ashpublications.org
Allergic, inflammatory, and immune responses carried out by eosinophils are regulated by
the cross talk between activatory and inhibitory signals. While much data has been obtained …

[HTML][HTML] Thought-controlled nanoscale robots in a living host

…, L Ben-Ami, Y Amir, Y Hel-Or, D Friedman, I Bachelet - PloS one, 2016 - journals.plos.org
We report a new type of brain-machine interface enabling a human operator to control
nanometer-size robots inside a living animal by brain activity. Recorded EEG patterns are …

Mast cells as effector cells: a co-stimulating question

I Bachelet, F Levi-Schaffer - Trends in immunology, 2007 - cell.com
Mast cells are currently recognized as effector cells in many settings beyond just allergic
reactions, including innate immunity, autoimmunity, chronic inflammatory disorders and …

Visualizing the structure and motion of the long noncoding RNA HOTAIR

…, J Giron, R Unger, E Segal, A Abu-Horowitz, I Bachelet - Rna, 2020 - rnajournal.cshlp.org
Long noncoding RNA molecules (lncRNAs) are estimated to account for the majority of
eukaryotic genomic transcripts, and have been associated with multiple diseases in humans. …

Targeting an antimicrobial effector function in insect immunity as a pest control strategy

MS Bulmer, I Bachelet, R Raman… - Proceedings of the …, 2009 - National Acad Sciences
Insect pests such as termites cause damages to crops and man-made structures estimated
at over $30 billion per year, imposing a global challenge for the human economy. Here, we …