User profiles for Ignacio Sanz

Ignacio Sanz

- Verified email at emory.edu - Cited by 21079

IGNACIO SANZ SANCHEZ

- Verified email at ucm.es - Cited by 6008

Hiperplasia benigna de próstata: una afección de elevada prevalencia en el paciente de edad avanzada

MF Arjona, IP Sanz - Revista Española de Geriatría y Gerontología, 2008 - Elsevier
En esta revisión pretendemos dar una visión de conjunto de una afección que, como veremos,
afecta a un porcentaje muy elevado de la población. Las diversas teorías que existen en …

[HTML][HTML] Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19

…, JE Crowe Jr, WT Hu, FEH Lee, I Sanz - Nature …, 2020 - nature.com
A wide spectrum of clinical manifestations has become a hallmark of the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) COVID-19 pandemic, although the …

[HTML][HTML] Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein

…, L Myers, F Eun-Hyung Lee, DC Nguyen, I Sanz… - Nature medicine, 2020 - nature.com
Antibodies are a principal determinant of immunity for most RNA viruses and have promise
to reduce infection or disease during major epidemics. The novel coronavirus SARS-CoV-2 …

[HTML][HTML] Identification of a B cell signature associated with renal transplant tolerance in humans

…, WJ Burlingham, WH Marks, I Sanz… - The Journal of …, 2010 - Am Soc Clin Investig
Establishing long-term allograft acceptance without the requirement for continuous
immunosuppression, a condition known as allograft tolerance, is a highly desirable therapeutic goal …

[PDF][PDF] Distinct effector B cells induced by unregulated toll-like receptor 7 contribute to pathogenic responses in systemic lupus erythematosus

…, G Gibson, FEH Lee, JM Boss, FE Lund, I Sanz - Immunity, 2018 - cell.com
Systemic Lupus Erythematosus (SLE) is characterized by B cells lacking IgD and CD27 (double
negative; DN). We show that DN cell expansions reflected a subset of CXCR5 - CD11c + …

Management of peri‐implant mucositis and peri‐implantitis

…, F Graziani, I Sanz, D Herrera, M Sanz - Periodontology …, 2014 - Wiley Online Library
Peri‐implant diseases are defined as inflammatory lesions of the surrounding peri‐implant
tissues and include peri‐implant mucositis (an inflammatory lesion limited to the surrounding …

[HTML][HTML] Challenges and opportunities for consistent classification of human B cell and plasma cell populations

I Sanz, C Wei, SA Jenks, KS Cashman… - Frontiers in …, 2019 - frontiersin.org
The increasingly recognized role of different types of B cells and plasma cells in protective
and pathogenic immune responses combined with technological advances have generated a …

[HTML][HTML] Dysregulated naive B cells and de novo autoreactivity in severe COVID-19

…, CL Maier, A Esper, SA Jenks, FEH Lee, I Sanz - Nature, 2022 - nature.com
Severe SARS-CoV-2 infection 1 has been associated with highly inflammatory immune
activation since the earliest days of the COVID-19 pandemic 2 , 3 , 4 – 5 . More recently, these …

[HTML][HTML] Advances in human B cell phenotypic profiling

…, C Wei, Y Qian, AF Rosenberg, I Sanz - Frontiers in …, 2012 - frontiersin.org
To advance our understanding and treatment of disease, research immunologists have
been called-upon to place more centralized emphasis on impactful human studies. Such …

[HTML][HTML] Chronic inflammation, neutrophil activity, and autoreactivity splits long COVID

…, JS Knight, A Khosroshahi, FEH Lee, I Sanz - Nature …, 2023 - nature.com
While immunologic correlates of COVID-19 have been widely reported, their associations
with post-acute sequelae of COVID-19 (PASC) remain less clear. Due to the wide array of …