Background Chronic neuroinflammation is a hallmark of Parkinson’s disease (PD) pathophysiology,
associated with increased levels of pro-inflammatory factors in PD brain tissues. The …

Autoantibodies to Parkinson’s disease (PD) amyloidogenic protein, α-synuclein, were
recognized as a prospective biomarker for early disease diagnostics, yet there is inconsistency in …

Quantitative kinetic analysis is critical for understanding amyloid mechanisms. Here we
demonstrate the application of generic Finke–Watzky (FW) two-step nucleation–autocatalytic …

Pro-inflammatory and amyloidogenic S100A9 protein is an important contributor to Alzheimer’s
disease (AD) pathology. Traumatic brain injury (TBI) is viewed as a precursor state for AD…

Polyphenolic compounds in the Mediterranean diet have received increasing attention due
to their protective properties in amyloid neurodegenerative and many other diseases. Here, …

Alzheimer’s disease (AD) is the most common cause of dementia worldwide. AD brains
display deposits of insoluble amyloid plaques consisting mainly of aggregated amyloid-β (Aβ) …

Dysregulation of the biosynthesis of cholesterol and other lipids has been implicated in
many neurological diseases, including Parkinson's disease. Misfolding of α‐synuclein (α‐Syn), …

Pro-inflammatory and amyloidogenic S100A9 protein is central to the amyloid-neuroinflammatory
cascade in neurodegenerative diseases. Polyoxometalates (POMs) constitute a …

Xylem fibers are highly elongated cells that are key constituents of wood, play major
physiological roles in plants, comprise an important terrestrial carbon reservoir, and thus have …

The mechanism of amyloid co-aggregation and its nucleation process are not fully understood
in spite of extensive studies. Deciphering the interactions between proinflammatory …