Means for high-density multiparametric physiological mapping and stimulation are critically
important in both basic and clinical cardiology. Current conformal electronic systems are …

Temporary cardiac pacemakers used in periods of need during surgical recovery involve
percutaneous leads and externalized hardware that carry risks of infection, constrain patient …

Rationale: The mechanistic basis for cardiac and renal dysfunction in sepsis is unknown. In
particular, the degree and type of cell death is undefined. Objectives: To evaluate the degree …

Optical techniques have revolutionized the investigation of cardiac cellular physiology and
advanced our understanding of basic mechanisms of electrical activity, calcium homeostasis, …

BACKGROUND: Application of fluorescence imaging of cardiac electrical activity is limited
by motion artifacts and/or side effects of currently available pharmacologic excitation–…

Rationale: Transmural dispersion of repolarization has been shown to play a role in the
genesis of ventricular tachycardia and fibrillation in different animal models of heart failure (HF). …

Flexible electronic/optoelectronic systems that can intimately integrate onto the surfaces of
vital organ systems have the potential to offer revolutionary diagnostic and therapeutic …

Temporary postoperative cardiac pacing requires devices with percutaneous leads and
external wired power and control systems. This hardware introduces risks for infection, …

The rigidity and relatively primitive modes of operation of catheters equipped with sensing or
actuation elements impede their conformal contact with soft-tissue surfaces, limit the scope …

Delivery of a strong electric shock to the heart remains the only effective therapy against
ventricular fibrillation. Despite significant improvements in implantable cardioverter defibrillator (…