Alzheimer's disease (AD) is characterized by specific alterations of brain DNA methylation (DNAm)
patterns. Age and sex, two major risk factors for AD, are also known to largely affect …

XAI is a rapidly progressing field of machine learning, aiming to unravel the predictions of
complex models. XAI is especially required in sensitive applications, eg in health care, when …

The existence of a sex gap in human health and longevity has been widely documented.
Autosomal DNA methylation differences between males and females have been reported, but …

We report Lobachevsky University Database (LUDB) of ECG signals, an open tool for validating
ECG delineation algorithms, that is superior to the existing publicly available data bases …

Chronic kidney disease (CKD) is defined by a reduced estimated glomerular filtration rate (eGFR).
This failure can be related to a phenotype of accelerated aging. In this work, we …

We propose a new algorithm for determining the basic significant points of various
electrocardiographic-signal waves taking into account information from all available leads and …

Lobachevsky University Electrocardiography Database (LUDB) is an ECG signal database
with marked boundaries and peaks of P, T waves and QRS complexes. The database …

Background DNA methylation has a significant effect on gene expression and can be
associated with various diseases. Meta-analysis of available DNA methylation datasets requires …

Background The aging process affects all systems of the human body, and the observed
increase in inflammatory components affecting the immune system in old age can lead to the …

Background Yakuts are one of the indigenous populations of the subarctic and arctic territories
of Siberia characterized by a continental subarctic climate with severe winters, with the …