User profiles for Ijeoma Nwabudike
Ijeoma NwabudikeVerified email at yale.edu Cited by 155 |
[PDF][PDF] High-throughput functional analysis of autism genes in zebrafish identifies convergence in dopaminergic and neuroimmune pathways
…, C Sakai, C Szi, B Rooney, M Ghosh, I Nwabudike… - Cell reports, 2023 - cell.com
Advancing from gene discovery in autism spectrum disorders (ASDs) to the identification of
biologically relevant mechanisms remains a central challenge. Here, we perform parallel in …
biologically relevant mechanisms remains a central challenge. Here, we perform parallel in …
[PDF][PDF] ASICs mediate food responses in an enteric serotonergic neuron that controls foraging behaviors
Animals must respond to the ingestion of food by generating adaptive behaviors, but the
role of gut-brain signaling in behavioral regulation is poorly understood. Here, we identify …
role of gut-brain signaling in behavioral regulation is poorly understood. Here, we identify …
[PDF][PDF] Dissecting the functional organization of the C. elegans serotonergic system at whole-brain scale
Serotonin influences many aspects of animal behavior. But how serotonin acts on its diverse
receptors across the brain to modulate global activity and behavior is unknown. Here, we …
receptors across the brain to modulate global activity and behavior is unknown. Here, we …
A neural circuit for flexible control of persistent behavioral states
To adapt to their environments, animals must generate behaviors that are closely aligned to
a rapidly changing sensory world. However, behavioral states such as foraging or courtship …
a rapidly changing sensory world. However, behavioral states such as foraging or courtship …
Functional Analysis of Autism Genes in Zebrafish Identifies Convergence in Dopaminergic and Neuroimmune Pathways and Pharmacological Candidates.
…, C Szi, B Rooney, M Ghosh, I Nwabudike - Gazi Medical …, 2024 - search.ebscohost.com
A central challenge in the genetics of autism spectrum disorders (ASDs) is advancing from
gene discovery to the identification of actionable biological mechanisms. To investigate the …
gene discovery to the identification of actionable biological mechanisms. To investigate the …
Genetic and Neural Circuit Analyses of Sickness and Foraging Behaviors in C. elegans
GK Madan - 2024 - dspace.mit.edu
… D.; Talya Kramer for her perceptive takes on science and life in general; and Ijeoma
Nwabudike for her engaging company and wide-ranging discussions that often extended late into …
Nwabudike for her engaging company and wide-ranging discussions that often extended late into …
[PDF][PDF] Physicochemical properties, total concentration, geochemical fractions, and health risks of trace metals in oilbearing soils of Akwa Ibom State, Nigeria
GA Ebong, EA Moses, OA Akpabio… - Journal of Materials & …, 2022 - academia.edu
The physicochemical properties, total metal, metal fractions, and related human health
problems of metals in oilbearing soils of Akwa Ibom State were appraised using standard …
problems of metals in oilbearing soils of Akwa Ibom State were appraised using standard …
In vivo Perturb-Seq reveals neuronal and glial abnormalities associated with autism risk genes
INTRODUCTION Human genetic studies have revealed long lists of genes and loci associated
with risk for many diseases and disorders, but to systematically evaluate their phenotypic …
with risk for many diseases and disorders, but to systematically evaluate their phenotypic …
Cell type-specific contributions to a persistent aggressive internal state in female Drosophila
Persistent internal states are important for maintaining survival-promoting behaviors, such
as aggression. In female Drosophila melanogaster, we have previously shown that …
as aggression. In female Drosophila melanogaster, we have previously shown that …
The CHD8/CHD7/Kismet family links blood-brain barrier glia and serotonin to ASD-associated sleep defects
M Coll-Tané, NN Gong, SJ Belfer, LV van Renssen… - Science …, 2021 - science.org
Sleep disturbances in autism and neurodevelopmental disorders are common and adversely
affect patient’s quality of life, yet the underlying mechanisms are understudied. We found …
affect patient’s quality of life, yet the underlying mechanisms are understudied. We found …