[HTML][HTML] Clinical sequencing uncovers origins and evolution of Lassa virus
The 2013–2015 West African epidemic of Ebola virus disease (EVD) reminds us of how little
is known about biosafety level 4 viruses. Like Ebola virus, Lassa virus (LASV) can cause …
is known about biosafety level 4 viruses. Like Ebola virus, Lassa virus (LASV) can cause …
[HTML][HTML] Molecular diagnostics for lassa fever at Irrua specialist teaching hospital, Nigeria: lessons learnt from two years of laboratory operation
DA Asogun, DI Adomeh, J Ehimuan, I Odia, M Hass… - 2012 - journals.plos.org
Background Lassa fever is a viral hemorrhagic fever endemic in West Africa. However, none
of the hospitals in the endemic areas of Nigeria has the capacity to perform Lassa virus …
of the hospitals in the endemic areas of Nigeria has the capacity to perform Lassa virus …
[HTML][HTML] Enhanced methods for unbiased deep sequencing of Lassa and Ebola RNA viruses from clinical and biological samples
…, SK Gire, E England, LM Moses, TS Mikkelsen, I Odia… - Genome biology, 2014 - Springer
We have developed a robust RNA sequencing method for generating complete de novo
assemblies with intra-host variant calls of Lassa and Ebola virus genomes in clinical and …
assemblies with intra-host variant calls of Lassa and Ebola virus genomes in clinical and …
A year of genomic surveillance reveals how the SARS-CoV-2 pandemic unfolded in Africa
…, HA Elgahzaly, H Gumbo, I Smeti, IB Ayed, I Odia… - Science, 2021 - science.org
The progression of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
pandemic in Africa has so far been heterogeneous, and the full impact is not yet well understood…
pandemic in Africa has so far been heterogeneous, and the full impact is not yet well understood…
[HTML][HTML] Discovery of novel rhabdoviruses in the blood of healthy individuals from West Africa
…, OA Folarin, JN Grove, I Odia… - PLoS neglected …, 2015 - journals.plos.org
Next-generation sequencing (NGS) has the potential to transform the discovery of viruses
causing unexplained acute febrile illness (UAFI) because it does not depend on culturing the …
causing unexplained acute febrile illness (UAFI) because it does not depend on culturing the …
[HTML][HTML] Most neutralizing human monoclonal antibodies target novel epitopes requiring both Lassa virus glycoprotein subunits
…, MA Vandi, M Gbetuwa, O Ikponmwosa… - Nature …, 2016 - nature.com
Lassa fever is a severe multisystem disease that often has haemorrhagic manifestations. The
epitopes of the Lassa virus (LASV) surface glycoproteins recognized by naturally infected …
epitopes of the Lassa virus (LASV) surface glycoproteins recognized by naturally infected …
[HTML][HTML] Deployable CRISPR-Cas13a diagnostic tools to detect and report Ebola and Lassa virus cases in real-time
Recent outbreaks of viral hemorrhagic fevers (VHFs), including Ebola virus disease (EVD)
and Lassa fever (LF), highlight the urgent need for sensitive, deployable tests to diagnose …
and Lassa fever (LF), highlight the urgent need for sensitive, deployable tests to diagnose …
[HTML][HTML] Genomic analysis of Lassa virus during an increase in cases in Nigeria in 2018
During 2018, an unusual increase in Lassa fever cases occurred in Nigeria, raising concern
among national and international public health agencies. We analyzed 220 Lassa virus …
among national and international public health agencies. We analyzed 220 Lassa virus …
Clinical and laboratory predictors of Lassa fever outcome in a dedicated treatment facility in Nigeria: a retrospective, observational cohort study
…, E Ediale, M Rafiu, D Adomeh, I Odia… - The Lancet Infectious …, 2018 - thelancet.com
Background Lassa fever is a viral haemorrhagic disease endemic to west Africa. No large-scale
studies exist from Nigeria, where the Lassa virus (LASV) is most diverse. LASV diversity, …
studies exist from Nigeria, where the Lassa virus (LASV) is most diverse. LASV diversity, …
[HTML][HTML] Capturing sequence diversity in metagenomes with comprehensive and scalable probe design
…, LM Paul, AL Tan, KF Garcia, LA Parham, I Odia… - Nature …, 2019 - nature.com
Metagenomic sequencing has the potential to transform microbial detection and
characterization, but new tools are needed to improve its sensitivity. Here we present CATCH, a …
characterization, but new tools are needed to improve its sensitivity. Here we present CATCH, a …