The impact of complex II (succinate:ubiquinone oxidoreductase) on the mitochondrial production
of reactive oxygen species (ROS) has been underestimated for a long time. However, …

A variety of chemicals can be produced in a living host cell via optimized and engineered
biosynthetic pathways. Despite the successes, pathway engineering remains demanding …

Manganese-induced toxicity has been linked to mitochondrial dysfunction and an increased
generation of reactive oxygen species (ROS). We could recently show in mechanistic …

The charge translocation by purified reconstituted mitochondrial complex I from the obligate
aerobic yeast Yarrowia lipolytica was investigated after adsorption of proteoliposomes to …

Telomerase prevents aging and is important for synthesis and maintenance of telomere
length in the nucleus. The catalytic subunit, the telomerase reverse transcriptase (TERT), has …

The mitochondrial respiratory chain is a major source of cellular reactive oxygen species (ROS).
Recent data indicate that beside the established H 2 O 2 /O 2 ●– -generators NADH-…

… Author links open overlay panel Lea Bleier a , Ilka Wittig a b , Heinrich Heide a , Mirco Steger
a , Ulrich … We thank Ilka Siebels and Maximillian Mattil for excellent technical assistance. …

The mitochondrial electron transport chain (ETC) is a part of the oxidative phosphorylation (OXPHOS)
metabolic pathway. Its components catalyze the transfer of electrons from …

Clear native electrophoresis and blue native electrophoresis are microscale techniques for
the isolation of membrane protein complexes. The Coomassie Blue G-250 dye, used in blue …

… We are grateful for excellent technical assistance of Ilka Siebels, Gudrun Beyer, and Maximillian
Mattil. Funding by the Deutsche Forschungsgemeinschaft (SFB815 Projects A2, Z1) and …