Inhibition of fibroblast growth factor 19 reduces tumor growth by modulating β-catenin signaling

R Pai, D Dunlap, J Qing, I Mohtashemi, K Hotzel… - Cancer research, 2008 - AACR
Fibroblast growth factors (FGF) play important roles in development, angiogenesis, and
cancer. FGF19 uniquely binds to FGF receptor 4 (FGFR4). Our previous study has shown that …

Mass Spectral Analysis of Neuropeptide Expression and Distribution in the Nervous System of the Lobster Homarus americanus

…, MC Prieto Conaway, I Mohtashemi… - Journal of proteome …, 2010 - ACS Publications
The lobster Homarus americanus has long served as an important animal model for
electrophysiological and behavioral studies. Using this model, we performed a comprehensive …

[HTML][HTML] Functionally distinct BMP1 isoforms show an opposite pattern of abundance in plasma from non-small cell lung cancer subjects and controls

…, J Wang, D Hornburg, S Ferdosi, I Mohtashemi… - Plos one, 2023 - journals.plos.org
Advancements in deep plasma proteomics are enabling high-resolution measurement of
plasma proteoforms, which may reveal a rich source of novel biomarkers previously concealed …

Peptide-centric analyses of human plasma enable increased resolution of biological insights into non-small cell lung cancer relative to protein-centric analysis

…, JE Blume, J Wang, D Hornburg, I Mohtashemi… - Biorxiv, 2022 - biorxiv.org
Comprehensive assessment of the human proteome remains challenging due to multiple
forms of a protein, or proteoforms, arising from alternative splicing, allelic variation, and protein …

[PDF][PDF] Rapid Proteomics Analysis Algorithm Development Using Proteome Discoverer Software: A Development Environment for Proteomics Scientists

I Mohtashemi, K Fritzemeier, H Grensemann… - apps.thermoscientific.com
Purpose: Here we present Thermo Scientific Proteome Discoverer software, a nodebased
framework for proteomics data processing. We will explain the general structure of the …

[PDF][PDF] Peptide-centric analyses of human plasma enable increased resolution of biological insights into non-small cell

…, JE Blume, J Wang, D Hornburg, I Mohtashemi - complexity, 2014 - media.seer.bio
Comprehensive assessment of the human proteome remains challenging due to multiple
forms of a protein, or proteoforms, arising from alternative splicing, allelic variation, and protein …

Alteration of the lipid profile in lymphomas induced by MYC overexpression

LS Eberlin, M Gabay, AC Fan… - Proceedings of the …, 2014 - National Acad Sciences
… We thank Mari Prieto Conaway and Iman Mohtashemi from Thermo Fisher Scientific for the
custom-built software tools provided. RJT is supported by National Science Foundation Grant …

Advances in bioanalytical LC–MS using the Orbitrap™ mass analyzer

M Scigelova, A Makarov - Bioanalysis, 2009 - Future Science
… Catharina Crone, Markus Kellmann, Helmut Muenster, Iman Mohtashemi and Mari Prieto
are gratefully acknowledged for providing figures illustrating the capabilities of the Orbitrap in …

Efficient removal of detergents from proteins and peptides in a spin column format

BS Antharavally, KA Mallia, MM Rosenblatt… - Analytical …, 2011 - Elsevier
Detergents are commonly used in protein–chemistry protocols and may be necessary for
protein extraction, solubilization, and denaturation; however, their presence interferes with …

[CITATION][C] Identification and Relative Quantitation of Peptides in Complex Un-fractionated Serum Matrices Using MALDI LTQ Orbitrap XL

R Viner, I Mohtashemi, ER Remily, J Koomen