Pulmonary CCL18 recruits human regulatory T cells
C Chenivesse, Y Chang, I Azzaoui… - The Journal of …, 2012 - journals.aai.org
CCL18 is both a constitutively expressed and an inducible chemokine, whose role in the
inflammatory reaction is poorly known. The aim of this study was to evaluate whether CCL18 …
inflammatory reaction is poorly known. The aim of this study was to evaluate whether CCL18 …
[HTML][HTML] High-affinity autoreactive plasma cells disseminate through multiple organs in patients with immune thrombocytopenic purpura
The major therapeutic goal for immune thrombocytopenic purpura (ITP) is to restore normal
platelet counts using drugs to promote platelet production or by interfering with mechanisms …
platelet counts using drugs to promote platelet production or by interfering with mechanisms …
[PDF][PDF] Maturation and persistence of the anti-SARS-CoV-2 memory B cell response
…, G Barba-Spaeth, A Roeser, S Fourati, I Azzaoui… - Cell, 2021 - cell.com
Memory B cells play a fundamental role in host defenses against viruses, but to date, their
role has been relatively unsettled in the context of SARS-CoV-2. We report here a longitudinal …
role has been relatively unsettled in the context of SARS-CoV-2. We report here a longitudinal …
[PDF][PDF] mRNA vaccination of naive and COVID-19-recovered individuals elicits potent memory B cells that recognize SARS-CoV-2 variants
…, G Barba-Spaeth, I Fernández, M Broketa, I Azzaoui… - Immunity, 2021 - cell.com
In addition to serum immunoglobulins, memory B cell (MBC) generation against severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) is another layer of immune protection, …
respiratory syndrome coronavirus 2 (SARS-CoV-2) is another layer of immune protection, …
Early expansion of circulating granulocytic myeloid-derived suppressor cells predicts development of nosocomial infections in patients with sepsis
F Uhel, I Azzaoui, M Grégoire, C Pangault… - American journal of …, 2017 - atsjournals.org
Rationale: Sepsis induces a sustained immune dysfunction responsible for poor outcome
and nosocomial infections. Myeloid-derived suppressor cells (MDSCs) described in cancer …
and nosocomial infections. Myeloid-derived suppressor cells (MDSCs) described in cancer …
T-cell defect in diffuse large B-cell lymphomas involves expansion of myeloid-derived suppressor cells
I Azzaoui, F Uhel, D Rossille, C Pangault… - Blood, The Journal …, 2016 - ashpublications.org
In diffuse large B-cell lymphoma (DLBCL), the number of circulating monocytes and neutrophils
represents an independent prognostic factor. These cell subsets include monocytic and …
represents an independent prognostic factor. These cell subsets include monocytic and …
Analysis of mRNA vaccination-elicited RBD-specific memory B cells reveals strong but incomplete immune escape of the SARS-CoV-2 Omicron variant
…, A Meola, I Fernández, S Fourati, I Azzaoui… - Immunity, 2022 - cell.com
The SARS-CoV-2 Omicron variant can escape neutralization by vaccine-elicited and
convalescent antibodies. Memory B cells (MBCs) represent another layer of protection against …
convalescent antibodies. Memory B cells (MBCs) represent another layer of protection against …
Human type I IFN deficiency does not impair B cell response to SARS-CoV-2 mRNA vaccination
Inborn and acquired deficits of type I interferon (IFN) immunity predispose to life-threatening
COVID-19 pneumonia. We longitudinally profiled the B cell response to mRNA vaccination …
COVID-19 pneumonia. We longitudinally profiled the B cell response to mRNA vaccination …
Rituximab-resistant splenic memory B cells and newly engaged naive B cells fuel relapses in patients with immune thrombocytopenia
…, P Chappert, A Sokal, S Weller, I Azzaoui… - Science translational …, 2021 - science.org
Rituximab (RTX), an antibody targeting CD20, is widely used as a first-line therapeutic strategy
in B cell–mediated autoimmune diseases. However, a large proportion of patients either …
in B cell–mediated autoimmune diseases. However, a large proportion of patients either …
SARS-CoV-2 Omicron BA. 1 breakthrough infection drives late remodeling of the memory B cell repertoire in vaccinated individuals
…, I Fernández, M Broketa, A Meola, S Fourati, I Azzaoui… - Immunity, 2023 - cell.com
How infection by a viral variant showing antigenic drift impacts a preformed mature human
memory B cell (MBC) repertoire remains an open question. Here, we studied the MBC …
memory B cell (MBC) repertoire remains an open question. Here, we studied the MBC …