User profiles for Inés Pineda-Torra
 | Inés Pineda TorraProfessor in Cardiometabolic Medicine Verified email at ucl.ac.uk Cited by 12893 |
Bile acids induce the expression of the human peroxisome proliferator-activated receptor α gene via activation of the farnesoid X receptor
I Pineda Torra, T Claudel, C Duval… - Molecular …, 2003 - academic.oup.com
Peroxisome proliferator-activated receptor α (PPARα) is a nuclear receptor that controls lipid
and glucose metabolism and exerts antiinflammatory activities. PPARα is also reported to …
and glucose metabolism and exerts antiinflammatory activities. PPARα is also reported to …
Activation of human aortic smooth-muscle cells is inhibited by PPARα but not by PPARγ activators
Peroxisome proliferator-activated receptors (PPARs) are key players in lipid and glucose
metabolism and are implicated in metabolic disorders predisposing to atherosclerosis, such as …
metabolism and are implicated in metabolic disorders predisposing to atherosclerosis, such as …
PPAR-α and PPAR-γ activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway
G Chinetti, S Lestavel, V Bocher, AT Remaley… - Nature medicine, 2001 - nature.com
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that regulate
lipid and glucose metabolism and cellular differentiation. PPAR-α and PPAR-γ are both …
lipid and glucose metabolism and cellular differentiation. PPAR-α and PPAR-γ are both …
[HTML][HTML] Activation of proliferator-activated receptors α and γ induces apoptosis of human monocyte-derived macrophages
G Chinetti, S Griglio, M Antonucci, IP Torra… - Journal of Biological …, 1998 - ASBMB
Peroxisome proliferator-activated receptors (PPARs) have been implicated in metabolic
diseases, such as obesity, diabetes, and atherosclerosis, due to their activity in liver and …
diseases, such as obesity, diabetes, and atherosclerosis, due to their activity in liver and …
Estrogen-related receptor α directs peroxisome proliferator-activated receptor α signaling in the transcriptional control of energy metabolism in cardiac and skeletal …
Estrogen-related receptors (ERRs) are orphan nuclear receptors activated by the transcriptional
coactivator peroxisome proliferator-activated receptor γ (PPARγ) coactivator 1α (PGC-1α…
coactivator peroxisome proliferator-activated receptor γ (PPARγ) coactivator 1α (PGC-1α…
[HTML][HTML] Bile acid-activated nuclear receptor FXR suppresses apolipoprotein AI transcription via a negative FXR response element
T Claudel, E Sturm, H Duez, IP Torra… - The Journal of …, 2002 - Am Soc Clin Investig
Serum levels of HDL are inversely correlated with the risk of coronary heart disease. The
anti-atherogenic effect of HDL is partially mediated by its major protein constituent apoA-I. In …
anti-atherogenic effect of HDL is partially mediated by its major protein constituent apoA-I. In …
Regulation of lipid and lipoprotein metabolism by PPAR activators
The peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription
factors belonging to the nuclear hormone receptor superfamily. PPARα, the first identified …
factors belonging to the nuclear hormone receptor superfamily. PPARα, the first identified …
PPARs: transcription factors controlling lipid and lipoprotein metabolism
V Bocher, I PINEDA‐TORRA… - Annals of the New …, 2002 - Wiley Online Library
Nuclear receptors are transcription factors that are activated by ligands and subsequently
bind to regulatory regions in target genes, thereby modulating their expression. Nuclear …
bind to regulatory regions in target genes, thereby modulating their expression. Nuclear …
Characterization of the human PPARα promoter: identification of a functional nuclear receptor response element
I Pineda Torra, Y Jamshidi, DM Flavell… - Molecular …, 2002 - academic.oup.com
PPARα is a nuclear receptor that controls lipid and glucose metabolism and exerts antiinflammatory
activities. The factors regulating human PPARα (hPPARα) gene expression remain …
activities. The factors regulating human PPARα (hPPARα) gene expression remain …
Peroxisome proliferator-activated receptor α gene variants influence progression of coronary atherosclerosis and risk of coronary artery disease
DM Flavell, Y Jamshidi, E Hawe, I Pineda Torra… - Circulation, 2002 - Am Heart Assoc
Background— Peroxisome proliferator-activated receptor α (PPARα) regulates the expression
of genes involved in lipid metabolism and inflammation, making it a candidate gene for …
of genes involved in lipid metabolism and inflammation, making it a candidate gene for …