Recent experimental and human studies have shown that hyperuricemia is associated with
hypertension, systemic inflammation, and cardiovascular disease mediated by endothelial …

AMP-activated protein kinase (AMPK) functions as a fuel sensor in the cell and is activated
when cellular energy is depleted. Here we report that α-lipoic acid (α-LA), a cofactor of …

OBJECTIVE—Low-level exposure to some persistent organic pollutants (POPs) has
recently become a focus because of their possible link with the risk of diabetes. RESEARCH …

OBJECTIVE—Metformin is an antidiabetic drug commonly used to treat type 2 diabetes. The
aim of the study was to determine whether metformin regulates hepatic gluconeogenesis …

The liver may regulate glucose homeostasis by modulating the sensitivity/resistance of
peripheral tissues to insulin, by way of the production of secretory proteins, termed hepatokines. …

Vascular calcification (VC), which is categorized by intimal and medial calcification, depending
on the site(s) involved within the vessel, is closely related to cardiovascular disease. …

OBJECTIVE—We reported strong relations between serum concentrations of persistent
organic pollutants (POPs), especially organochlorine (OC) pesticides or nondioxin-like …

The aim of this study was to investigate the relationship between adiponectin and leptin and
body fat distribution. One hundred and ninety-seven women participated in this study. …

Endoplasmic reticulum (ER)-bound transcription factor families are shown to be involved in
the control of various metabolic pathways. Here, we report a critical function of ER-bound …

Fatty liver is common in obese subjects with insulin resistance. Hepatic expression of sterol
regulatory element binding protein‐1c (SREBP‐1c), which plays a major role in hepatic …