User profiles for Ines Fragata

Inês Fragata

Centre for Ecology, Evolution and Environmental Changes
Verified email at fc.ul.pt
Cited by 955

Evolution in the light of fitness landscape theory

I Fragata, A Blanckaert, MAD Louro, DA Liberles… - Trends in ecology & …, 2019 - cell.com
By formalizing the relationship between genotype or phenotype and fitness, fitness landscapes
harbor information on molecular and evolutionary constraints. The shape of the fitness …

Keeping your options open: Maintenance of thermal plasticity during adaptation to a stable environment

I Fragata, M Lopes-Cunha, M Barbaro, B Kellen… - …, 2016 - academic.oup.com
Phenotypic plasticity may allow species to cope with environmental variation. The study of
thermal plasticity and its evolution helps understanding how populations respond to variation …

[HTML][HTML] Laboratory selection quickly erases historical differentiation

I Fragata, P Simoes, M Lopes-Cunha, M Lima… - PLoS …, 2014 - journals.plos.org
The roles of history, chance and selection have long been debated in evolutionary biology.
Though uniform selection is expected to lead to convergent evolution between populations, …

How chromosomal inversions reorient the evolutionary process

…, B Charlesworth, R Faria, I Fragata… - Journal of …, 2023 - Wiley Online Library
Inversions are structural mutations that reverse the sequence of a chromosome segment and
reduce the effective rate of recombination in the heterozygous state. They play a major role …

How repeatable is adaptive evolution? The role of geographical origin and founder effects in laboratory adaptation

P Simoes, J Santos, I Fragata, LD Mueller, MR Rose… - …, 2008 - academic.oup.com
The importance of contingency versus predictability in evolution has been a long-standing
issue, particularly the interaction between genetic background, founder effects, and selection. …

Unboxing mutations: Connecting mutation types with evolutionary consequences

…, T Slotte, A Suh, AM Westram, I Fragata - Molecular …, 2021 - Wiley Online Library
A key step in understanding the genetic basis of different evolutionary outcomes (eg,
adaptation) is to determine the roles played by different mutation types (eg, SNPs, translocations …

Climate change and chromosomal inversions in Drosophila subobscura

…, J Balanyà, F Rodríguez-Trelles, C Rego, I Fragata… - Climate …, 2010 - int-res.com
In natural populations, the large changes in chromosomal structure occurring through
chromosomal inversions show pronounced variations in frequency that often correspond to …

CLINAL PATTERNS OF CHROMOSOMAL INVERSION POLYMORPHISMS IN DROSOPHILA SUBOBSCURA ARE PARTLY ASSOCIATED WITH THERMAL …

C Rego, J Balanya, I Fragata, M Matos, EL Rezende… - …, 2010 - academic.oup.com
Latitudinal clines in the frequency of various chromosomal inversions are well documented
in Drosophila subobscura. Because these clines are roughly parallel on three continents, …

Comprehensive fitness maps of Hsp90 show widespread environmental dependence

JM Flynn, A Rossouw, P Cote-Hammarlof, I Fragata… - Elife, 2020 - elifesciences.org
Gene-environment interactions have long been theorized to influence molecular evolution.
However, the environmental dependence of most mutations remains unknown. Using deep …

[HTML][HTML] The utility of fitness landscapes and big data for predicting evolution

JAGM de Visser, SF Elena, I Fragata, S Matuszewski - Heredity, 2018 - nature.com
… for the mutations in Hsp90 of yeast by Fragata & Matuszewski et al. Together, these studies
… These authors contributed equally to the coordination of the editorial process: Inês Fragata, …