Cerebral small vessel disease (SVD) is a common accompaniment of ageing. Features
seen on neuroimaging include recent small subcortical infarcts, lacunes, white matter …

Histopathological studies in Alzheimer's disease (AD) suggest severe and region-specific
neurodegeneration of the basal forebrain cholinergic system (BFCS). Here, we studied the …

Objective To determine whether following a Mediterranean-like diet (MeDi) relates to
cognitive functions and in vivo biomarkers for Alzheimer disease (AD), we analyzed cross-sectional …

Background There is growing evidence in the literature that the cholinergic basal forebrain
might be one of the earliest affected structures in Alzheimer’s disease (AD). Recent data …

Background Deep phenotyping and longitudinal assessment of predementia at-risk states
of Alzheimer’s disease (AD) are required to define populations and outcomes for dementia …

Importance Dementia care management (DCM) can increase the quality of care for people
with dementia. Methodologically rigorous clinical trials on DCM are lacking. Objective To test …

Diffusion tensor imaging (DTI) based assessment of white matter fiber tract integrity can
support the diagnosis of Alzheimer’s disease (AD). The use of DTI as a biomarker, however, …

Background Subjective cognitive decline (SCD) has been proposed as a pre-MCI at-risk
condition of Alzheimer’s disease (AD). Current research is focusing on a refined assessment of …

Introduction This study aimed to assess how interindividual differences in locus coeruleus (LC)
magnetic resonance imaging (MRI) contrast relate to cerebrospinal fluid (CSF) …

Recent research has revealed an association between hearing impairment and dementia.
The objective of this study is to determine the effect of hearing impairment on dementia …