ELPylated anti‐human TNF therapeutic single‐domain antibodies for prevention of lethal septic shock

U Conrad, I Plagmann, S Malchow… - Plant biotechnology …, 2011 - Wiley Online Library
Tumour necrosis factor (TNF) is a major pro‐inflammatory cytokine involved in multiple
inflammatory diseases. The detrimental activity of TNF can be blocked by various antagonists, …

The proteomic landscape of small urinary extracellular vesicles during kidney transplantation

…, D Buchner, K Bohl, I Plagmann… - Journal of …, 2020 - Wiley Online Library
Kidney transplantation is the preferred renal replacement therapy available. Yet, long‐term
transplant survival is unsatisfactory, partially due to insufficient possibilities of longitudinal …

Super-resolution imaging of the filtration barrier suggests a role for podocin R229Q in genetic predisposition to glomerular disease

…, D Reilly, MM Rinschen, I Plagmann… - Journal of the …, 2022 - journals.lww.com
Background Diseases of the kidney’s glomerular filtration barrier are a leading cause of end
stage renal failure. Despite a growing understanding of genes involved in glomerular …

Transglutaminase-catalyzed covalent multimerization of Camelidae anti-human TNF single domain antibodies improves neutralizing activity

I Plagmann, A Chalaris, AA Kruglov… - Journal of …, 2009 - Elsevier
Tumor necrosis factor (TNF) plays an important role in chronic inflammatory disorders, such
as Rheumatoid Arthritis and Crohn's disease. Recently, monoclonal Camelidae variable …

[HTML][HTML] The podocytes' inflammatory responses in experimental GN are independent of canonical MYD88-dependent toll-like receptor signaling

T Schömig, P Diefenhardt, I Plagmann, B Trinsch… - Scientific Reports, 2024 - nature.com
Podocytes form the kidney filtration barrier and continuously adjust to external stimuli to
preserve their integrity even in the presence of inflammation. It was suggested that canonical toll-…

[HTML][HTML] Advanced optical imaging reveals preferred spatial orientation of podocyte processes along the axis of glomerular capillaries

D Unnersjö-Jess, A Ramdedovic, L Butt, I Plagmann… - Kidney International, 2023 - Elsevier
Mammalian kidneys filter enormous volumes of water and small solutes, a filtration driven by
the hydrostatic pressure in glomerular capillaries, which is considerably higher than in most …

Mechanical forces at the kidney filtration barrier govern spatial orientation of podocyte processes on capillaries

D Unnersjö-Jess, A Ramdedovic, L Butt, I Plagmann… - bioRxiv, 2023 - biorxiv.org
Mammalian kidneys filter enormous volumes of water and small solutes, a filtration driven
by the very high hydrostatic pressure in glomerular capillaries. Interdigitating cellular …

The proteome of small urinary extracellular vesicles after kidney transplantation as an indicator of renal cellular biology and a source for markers predicting outcome

…, C Klein, O Kretz, VG Puelles, D Bachurski, I Plagmann… - bioRxiv, 2019 - biorxiv.org
Kidney transplantation is the preferred renal replacement therapy available. Yet, the biological
processes during and after kidney transplantation and how they translate into the overall …

Efficacy of a remote web-based lung ultrasound training for nephrologists and cardiologists: a LUST trial sub-project

L Gargani, R Sicari, M Raciti, L Serasini… - Nephrology Dialysis …, 2016 - academic.oup.com
Within the framework of the LUST trial (LUng water by Ultra-Sound guided Treatment to
prevent death and cardiovascular events in high-risk end-stage renal disease patients), the …

[PDF][PDF] NDT Perspectives Efficacy of a remote web-based lung ultrasound training for nephrologists and cardiologists: a LUST trial sub-project

L Gargani, R Sicari, M Raciti, L Serasini, M Passera… - 2016 - academia.edu
Within the framework of the LUST trial (LUng water by Ultra-Sound guided Treatment to
prevent death and cardiovascular events in high-risk end-stage renal disease patients), the …