Asymptomatic malaria infections: detectability, transmissibility and public health relevance
Most Plasmodium falciparum infections that are detected in community surveys are
characterized by low-density parasitaemia and the absence of clinical symptoms. Molecular …
characterized by low-density parasitaemia and the absence of clinical symptoms. Molecular …
A Recombinant Blood-Stage Malaria Vaccine Reduces Plasmodium falciparum Density and Exerts Selective Pressure on Parasite Populations in a Phase 1-2b Trial …
B Genton, I Betuela, I Felger, F Al-Yaman… - The Journal of …, 2002 - academic.oup.com
The malaria vaccine Combination B comprises recombinant Plasmodium falciparum ring-infected
erythrocyte surface antigen and 2 merozoite surface proteins (MSP1 and MSP2) …
erythrocyte surface antigen and 2 merozoite surface proteins (MSP1 and MSP2) …
[HTML][HTML] Ultra-Sensitive Detection of Plasmodium falciparum by Amplification of Multi-Copy Subtelomeric Targets
…, S Shekalaghe, LJ Robinson, I Mueller, I Felger - PLoS …, 2015 - journals.plos.org
Background Planning and evaluating malaria control strategies relies on accurate definition
of parasite prevalence in the population. A large proportion of asymptomatic parasite …
of parasite prevalence in the population. A large proportion of asymptomatic parasite …
[PDF][PDF] Heterochromatin protein 1 secures survival and transmission of malaria parasites
…, R Wampfler, C Freymond, M Rottmann, I Felger… - Cell host & …, 2014 - cell.com
Clonally variant expression of surface antigens allows the malaria parasite Plasmodium
falciparum to evade immune recognition during blood stage infection and secure malaria …
falciparum to evade immune recognition during blood stage infection and secure malaria …
Identification and Differentiation of Leishmania Species in Clinical Samples by PCR Amplification of the Miniexon Sequence and Subsequent Restriction Fragment …
…, CL Jaffe, HP Beck, I Felger - Journal of clinical …, 2003 - Am Soc Microbiol
We recently developed a new PCR-restriction fragment length polymorphism (RFLP)-based
assay using the miniexon sequence from the genus Leishmania. Here we report the …
assay using the miniexon sequence from the genus Leishmania. Here we report the …
[HTML][HTML] Strategies for Detection of Plasmodium species Gametocytes
…, I Betuela, P Siba, HP Beck, I Mueller, I Felger - PloS one, 2013 - journals.plos.org
Carriage and density of gametocytes, the transmission stages of malaria parasites, are
determined for predicting the infectiousness of humans to mosquitoes. This measure is used for …
determined for predicting the infectiousness of humans to mosquitoes. This measure is used for …
[HTML][HTML] Strategies for Understanding and Reducing the Plasmodium vivax and Plasmodium ovale Hypnozoite Reservoir in Papua New Guinean Children: A …
…, Q Bassat, PM Siba, L Schofield, I Felger… - PLoS …, 2015 - journals.plos.org
Background The undetectable hypnozoite reservoir for relapsing Plasmodium vivax and P.
ovale malarias presents a major challenge for malaria control and elimination in endemic …
ovale malarias presents a major challenge for malaria control and elimination in endemic …
[HTML][HTML] Plasmodium falciparum msp1, msp2 and glurp allele frequency and diversity in sub-Saharan Africa
…, S Schoepflin, D Sumari, HP Beck, G Snounou, I Felger… - Malaria journal, 2011 - Springer
Background The efficacy of anti-malarial drugs is assessed over a period of 28-63 days (depending
on the drugs' residence time) following initiation of treatment in order to capture late …
on the drugs' residence time) following initiation of treatment in order to capture late …
Acquisition of antibodies against Plasmodium falciparum merozoites and malaria immunity in young children and the influence of age, force of infection, and …
…, JW Kazura, CL King, P Zimmerman, I Felger… - Infection and …, 2015 - Am Soc Microbiol
Individuals in areas of Plasmodium falciparum endemicity develop immunity to malaria after
repeated exposure. Knowledge of the acquisition and nature of protective immune …
repeated exposure. Knowledge of the acquisition and nature of protective immune …
Diagnostic genotyping of Old and New World Leishmania species by PCR-RFLP
…, I Niederwieser, ND Makia, HP Beck, I Felger - … and infectious disease, 2003 - Elsevier
We have designed a new genotyping scheme for molecular diagnosis of the different
Leishmania species pathogenic to humans. This scheme is based on PCR amplified sequences …
Leishmania species pathogenic to humans. This scheme is based on PCR amplified sequences …