Deep brain stimulation (DBS) of the nucleus basalis of Meynert (NBM) has been clinically
investigated in Alzheimer’s disease (AD) and Lewy body dementia (LBD). However, the …

Aging societies face an increasing prevalence of neurodegenerative disorders for which no
cure exists. The paucity of relevant animal models that faithfully reproduce clinical and …

Recently, a petition was offered to the European Commission calling for an immediate ban on
animal testing. Although a Europe-wide moratorium on the use of animals in science is not …

SARS-CoV-2 causes acute respiratory disease, but many patients also experience neurological
complications. Neuropathological changes with pronounced neuroinflammation have …

Study Objectives: Sleep problems are a common phenomenon in most neurological and
psychiatric diseases. In Parkinson disease (PD), for instance, sleep problems may be the most …

Background Coronavirus disease 2019 (COVID-19) patients initially develop respiratory
symptoms, but they may also suffer from neurological symptoms. People with long-lasting …

SARS-CoV-2 may cause acute respiratory disease, but the infection can also initiate neurological
symptoms. Here we show that SARS-CoV-2 infection causes brain inflammation in the …

Current therapies for Parkinson's disease (PD) like l-dopa and dopamine (DA) agonists
have declined efficacy after long term use. Therefore, research towards supplementary or …

It is known that rats poisoned with near-lethal doses of pinacolyl methylphosphonofluoridate
(soman) develop brain lesions, particularly when convulsions are induced. When rats were …

Due to the aging population, modern society is facing an increasing prevalence of
neurological diseases such as Alzheimer’s disease (AD). AD is an age-related chronic …