Liver is highly regenerative as it can restore its function and size even after 70% partial
hepatectomy. During liver regeneration, the mechanical and chemical environment of liver is …

Background and Aims Endoscopic submucosal dissection (ESD) and EMR are applied in
treating superficial colorectal neoplasms but are contraindicated by deeply invasive colorectal …

The symmetry breaking of protein distribution and cytoskeleton organization is an essential
aspect for the development of apicobasal polarity. In embryonic cells this process is largely …

Background & Aims A wide range of liver diseases manifest as biliary obstruction, or
cholestasis. However, the sequence of molecular events triggered as part of the early …

… Author links open overlay panel Kapish Gupta a , Inn Chuan Ng b , Gowri Manohari
Balachander b , Binh P. Nguyen c , Lisa Tucker-Kellogg d , Boon Chuan Low a e f , Hanry Yu a b f g …

Chemotaxis in shallow gradients of chemoattractants is accomplished by preferential
maintenance of protrusions oriented towards the chemoattractant; however, the mechanism of …

The TGF-β/Smad signaling system decreases its activity through strong negative regulation.
Several molecular mechanisms of negative regulation have been published, but the relative …

Cell-based in vitro models coupled with high-throughput transcriptomics (HTTr) are increasingly
utilized as alternative methods to animal-based toxicity testing. Here, using a panel of …

Primary hepatocytes are widely used in basic research on liver diseases and for toxicity testing
in vitro. The two-step collagenase perfusion procedure for primary hepatocyte isolation is …

A wide range of liver diseases manifest as biliary obstruction, or cholestasis. However, the
sequence of molecular events triggered as part of the early hepatocellular homeostatic …