The recent Zika virus outbreak highlights the need for low-cost diagnostics that can be rapidly
developed for distribution and use in pandemic regions. Here, we report a pipeline for the …

Mitigating global infectious disease requires diagnostic tools that are sensitive, specific, and
rapidly field deployable. In this study, we demonstrate that the Cas13-based SHERLOCK (…

Although the recent Zika virus (ZIKV) epidemic in the Americas and its link to birth defects
have attracted a great deal of attention 1 , 2 , much remains unknown about ZIKV disease …

An expansion of the cerebral neocortex is thought to be the foundation for the unique intellectual
abilities of humans. It has been suggested that an increase in the proliferative potential …

Rapid point-of-care (POC) diagnostic devices are needed for field-forward screening of
severe acute systemic febrile illnesses. Multiplexed rapid lateral flow diagnostics have the …

Background: Dengue fever is one of the most significant re-emerging tropical diseases,
despite our expanding knowledge of the disease, viral tropism is still not known to target heart …

The recent Zika virus (ZIKV) outbreak demonstrates that cost-effective clinical diagnostics
are urgently needed to detect and distinguish viral infections to improve patient care. Unlike …

The more severe form of dengue virus infection, dengue hemorrhagic fever, is characterized
by plasma leakage and derangements in hemostasis. As elevated interleukin-8 (IL-8) levels …

The resistance of human malignancy to multiple chemotherapeutic agents remains a major
obstacle in cancer therapy. Resistance has been termed intrinsic when the tumor initially fails …

Zika and dengue are mosquito-borne diseases that present similar nonspecific symptoms
but possess dramatically different outcomes. The first line of defense in epidemic outbreaks …