Extracellular matrix mechanical cues regulate lipid metabolism through Lipin-1 and SREBP

P Romani, I Brian, G Santinon, A Pocaterra… - Nature cell …, 2019 - nature.com
Extracellular matrix (ECM) mechanical cues have powerful effects on cell proliferation,
differentiation and death. Here, starting from an unbiased metabolomics approach, we identify …

d NTP metabolism links mechanical cues and YAP/TAZ to cell growth and oncogene‐induced senescence

G Santinon, I Brian, A Pocaterra, P Romani… - The EMBO …, 2018 - embopress.org
YAP / TAZ , downstream transducers of the Hippo pathway, are powerful regulators of cancer
growth. How these factors control proliferation remains poorly defined. Here, we found that …

F-actin dynamics regulates mammalian organ growth and cell fate maintenance

A Pocaterra, G Santinon, P Romani, I Brian… - Journal of …, 2019 - Elsevier
Background & Aims In vitro, cell function can be potently regulated by the mechanical
properties of cells and of their microenvironment. Cells measure these features by developing …

[HTML][HTML] Host response of Syrian Hamster to SARS-CoV-2 infection including differences with humans and between sexes

…, M Zorzan, P Drzewnioková, M Mancin, I Brian… - Viruses, 2023 - mdpi.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
highlighted the importance of having proper tools and models to study the pathophysiology of …

[HTML][HTML] Redesign and validation of a real-time RT-PCR to improve surveillance for avian influenza viruses of the H9 subtype

V Panzarin, S Marciano, A Fortin, I Brian, V D'Amico… - Viruses, 2022 - mdpi.com
Avian influenza viruses of the H9 subtype cause significant losses to poultry production in
endemic regions of Asia, Africa and the Middle East and pose a risk to human health. The …

Molecular Monitoring of SARS-CoV-2 in Different Sewage Plants in Venice and the Implications for Genetic Surveillance

I Brian, A Manuzzi, G Dalla Rovere, E Giussani… - Acs Es&T …, 2022 - ACS Publications
Wastewater-based epidemiology is now widely used as an indirect tool to monitor the spread
of SARS-CoV-2. In this study, five different sample matrices representing diverse phases of …

" That Unreasonable Restless Feeling": The Homosexual Subtexts of Nella Larsen's Passing

DL Blackmore - African American Review, 1992 - JSTOR
Irene and Clare and in the case of Brian. Behind the mask of their respectable middle-class
marriage, both Irene and Brian … They have separate bedrooms, and while Irene and Brian

Clare Kendry's" true" colors: Race and class conflict in Nella Larsen's passing

JDV Brody - Callaloo, 1992 - JSTOR
… and Brian Redfield are having an affair, then Irene's sympathy for … Irene's desire to spare
John's life as a symptom of Irene's … However, in my reading, Irene also sympathizes with John's …

Functional impact of global rare copy number variation in autism spectrum disorders

…, S Bölte, PF Bolton, T Bourgeron, S Brennan, J Brian… - Nature, 2010 - nature.com
The autism spectrum disorders (ASDs) are a group of conditions characterized by impairments
in reciprocal social interaction and communication, and the presence of restricted and …

Crosstalk between ECM mechanical cues and cellular metabolism

I Brian - 2019 - research.unipd.it
Mechanical cues coming from the extracellular matrix (ECM) are key factors in the control of
tissue homeostasis in physiology and disease. Cells can sense these physical cues and …