Salmonella enterica serovar Typhimurium is a facultative intracellular pathogen that causes
inflammation, necrosis, and diarrhea in pigs, as well as being an important source of food-…

The malaria parasite, Plasmodium, requires iron for growth, but how it imports iron remains
unknown. We characterize here a protein that belongs to the ZIP (Zrt‐, Irt‐like Protein) family …

Malaria remains an important parasitic disease with a large morbidity and mortality burden.
Plasmodium transmission-blocking (TB) compounds are essential for achieving malaria …

Malaria eradication requires the development of new drugs to combat drug-resistant parasites.
We identified bisbenzylisoquinoline alkaloids isolated from Cocculus hirsutus that are …

Epigenetic post-translational modifications are essential for human malaria parasite survival
and progression through its life cycle. Here, we present new functionalized suberoylanilide …

Malaria drug resistance is hampering the fight against the deadliest parasitic disease
affecting over 200 million people worldwide. We recently developed quinoline-quinazoline-based …

The lack of continuous in vitro cultures has been an obstacle delaying pre-clinical testing of
Plasmodium vivax vaccine formulations based on known antigens. In this study, we …

BACKGROUND Malaria is an infectious disease caused by protozoan parasites belonging to
the genus Plasmodium. Human-to-human transmission depends on a mosquito vector; thus…

Two years ago, we held an exciting event entitled the São Paulo School of Advanced Sciences
on Vaccines (SPSASV). Sixty-eight Ph.D. students, postdoctoral fellows and independent …

Malaria eradication requires the development of new drugs to combat drug-resistant parasites.
The search for new chemical scaffolds that target novel pathways of the human malaria …