User profiles for Irina R. Arkhipova

Irina Arkhipova

Marine Biological Laboratory
Verified email at mbl.edu
Cited by 4179

Massive horizontal gene transfer in bdelloid rotifers

EA Gladyshev, M Meselson, IR Arkhipova - science, 2008 - science.org
Horizontal gene transfer in metazoans has been documented in only a few species and is
usually associated with endosymbiosis or parasitism. By contrast, in bdelloid rotifers we found …

Telomere-associated endonuclease-deficient Penelope-like retroelements in diverse eukaryotes

EA Gladyshev, IR Arkhipova - Proceedings of the National …, 2007 - National Acad Sciences
The evolutionary origin of telomerases, enzymes that maintain the ends of linear chromosomes
in most eukaryotes, is a subject of debate. Penelope-like elements (PLEs) are a recently …

[HTML][HTML] Using bioinformatic and phylogenetic approaches to classify transposable elements and understand their complex evolutionary histories

IR Arkhipova - Mobile DNA, 2017 - Springer
In recent years, much attention has been paid to comparative genomic studies of transposable
elements (TEs) and the ensuing problems of their identification, classification, and …

Retroelements containing introns in diverse invertebrate taxa

IR Arkhipova, KI Pyatkov, M Meselson, MB Evgen'ev - Nature genetics, 2003 - nature.com
We report that two structurally similar transposable elements containing reverse transcriptase
(RT), Penelope in Drosophila virilis and Athena in bdelloid rotifers, have proliferated as …

[HTML][HTML] Bacterial N4-methylcytosine as an epigenetic mark in eukaryotic DNA

…, IA Yushenova, D DiCorpo, IR Arkhipova - Nature …, 2022 - nature.com
DNA modifications are used to regulate gene expression and defend against invading
genetic elements. In eukaryotes, modifications predominantly involve C5-methylcytosine (5mC) …

Neutral theory, transposable elements, and eukaryotic genome evolution

IR Arkhipova - Molecular biology and evolution, 2018 - academic.oup.com
Irina R Arkhipova Irina R Arkhipova … CDS, % genome covered by coding sequences (including
introns); R, regulatory regions; TE, transposable element sequences; S, high-copy …

A widespread class of reverse transcriptase-related cellular genes

EA Gladyshev, IR Arkhipova - Proceedings of the National …, 2011 - National Acad Sciences
Reverse transcriptases (RTs) polymerize DNA on RNA templates. They fall into several
structurally related but distinct classes and form an assemblage of RT-like enzymes that, in …

Three retrotransposon families in the genome of Giardia lamblia: Two telomeric, one dead

IR Arkhipova, HG Morrison - Proceedings of the National …, 2001 - National Acad Sciences
Transposable elements inhabiting eukaryotic genomes are generally regarded either as
selfish DNA, which is selectively neutral to the host organism, or as parasitic DNA, deleterious …

Giant transposons in eukaryotes: is bigger better?

IR Arkhipova, IA Yushenova - Genome biology and evolution, 2019 - academic.oup.com
Transposable elements (TEs) are ubiquitous in both prokaryotes and eukaryotes, and the
dynamic character of their interaction with host genomes brings about numerous evolutionary …

[HTML][HTML] Genomic signatures of recombination in a natural population of the bdelloid rotifer Adineta vaga

…, IA Yushenova, F Rodriguez, IR Arkhipova… - Nature …, 2020 - nature.com
Sexual reproduction is almost ubiquitous among extant eukaryotes. As most asexual lineages
are short-lived, abandoning sex is commonly regarded as an evolutionary dead end. Still, …