User profiles for Irina Spacova

Irina Spacova

Assistant professor, University of Antwerp
Verified email at uantwerpen.be
Cited by 834

[HTML][HTML] Future of probiotics and prebiotics and the implications for early career researchers

I Spacova, HB Dodiya, AU Happel, C Strain… - Frontiers in …, 2020 - frontiersin.org
The opportunities in the fields of probiotics and prebiotics to a great degree stem from what
we can learn about how they influence the microbiota and interact with the host. We discuss …

[HTML][HTML] Topical microbial therapeutics against respiratory viral infections

I Spacova, I De Boeck, PA Bron, P Delputte… - Trends in Molecular …, 2021 - cell.com
Emerging evidence suggests that microbial therapeutics can prevent and treat respiratory
viral diseases, especially when applied directly to the airways. This review presents …

[PDF][PDF] Lactobacilli have a niche in the human nose

…, MFL van den Broek, CN Allonsius, I Spacova… - Cell reports, 2020 - cell.com
Although an increasing number of beneficial microbiome members are characterized for the
human gut and vagina, beneficial microbes are underexplored for the human upper …

Lactobacillus rhamnosus probiotic prevents airway function deterioration and promotes gut microbiome resilience in a murine asthma model

I Spacova, W Van Beeck, S Seys, F Devos… - Gut …, 2020 - Taylor & Francis
… Petrova MI, van den Broek MFL, Spacova I, Verhoeven TLA, Balzarini J, Vanderleyden J,
Schols D, Lebeer S. Engineering Lactobacillus rhamnosus GG and GR-1 to express HIV-…

Lactic acid bacteria as probiotics for the nose?

I De Boeck, I Spacova, OM Vanderveken… - Microbial …, 2021 - Wiley Online Library
Several studies have recently pointed towards an increased occurrence and prevalence of
several taxa of the lactic acid bacteria (LAB) in the microbiota of the upper respiratory tract (…

The role of lactobacilli in inhibiting skin pathogens

L Delanghe, I Spacova, J Van Malderen… - Biochemical Society …, 2021 - portlandpress.com
The human skin microbiota forms a key barrier against skin pathogens and is important in
modulating immune responses. Recent studies identify lactobacilli as endogenous inhabitants …

[HTML][HTML] Comparing technology and regulatory landscape of probiotics as food, dietary supplements and live biotherapeutics

I Spacova, S Binda, JA Ter Haar, S Henoud… - Frontiers in …, 2023 - frontiersin.org
Application of beneficial microorganisms as probiotics targets a broad range of intended uses,
from maintaining health and supporting normal bodily functions to curing and preventing …

[HTML][HTML] Cotton and surgical face masks in community settings: bacterial contamination and face mask hygiene

L Delanghe, E Cauwenberghs, I Spacova… - Frontiers in …, 2021 - frontiersin.org
During the current COVID-19 pandemic, the use of face masks has become increasingly
recommended and even mandatory in community settings. To evaluate the risk of bacterial cross…

[PDF][PDF] Selective targeting of skin pathobionts and inflammation with topically applied lactobacilli

…, T Henkens, L Delanghe, S Wuyts, I Spacova… - Cell Reports …, 2022 - cell.com
Tailored skin microbiome modulation approaches with probiotics are highly challenging.
Here, we show that lactobacilli are underestimated members of the skin microbiota. We select …

Development of a live biotherapeutic throat spray with lactobacilli targeting respiratory viral infections

I Spacova, I De Boeck, E Cauwenberghs… - Microbial …, 2023 - Wiley Online Library
Development of a live biotherapeutic throat spray with lactobacilli targeting respiratory viral
infections - Spacova - 2023 … Irina Spacova and Ilke De Boeck contributed equally to this work. …