[HTML][HTML] Microenvironmental IL-6 inhibits anti-cancer immune responses generated by cytotoxic chemotherapy

EH Bent, LR Millán-Barea, I Zhuang, DR Goulet… - Nature …, 2021 - nature.com
Cytotoxic chemotherapeutics primarily function through DNA damage-induced tumor cell
apoptosis, although the inflammation provoked by these agents can stimulate anti-cancer …

Ionizable amphiphilic dendrimer‐based nanomaterials with alkyl‐chain‐substituted amines for tunable siRNA delivery to the liver endothelium in vivo

…, JM Pelet, MJ Webber, I Zhuang… - Angewandte Chemie …, 2014 - Wiley Online Library
A library of dendrimers was synthesized and optimized for targeted small interfering RNA (siRNA)
delivery to different cell subpopulations within the liver. Using a combinatorial …

[HTML][HTML] Optimized culture of retinal ganglion cells and amacrine cells from adult mice

YH Park, JD Snook, I Zhuang, G Shen, BJ Frankfort - PloS one, 2020 - journals.plos.org
Cell culture is widely utilized to study the cellular and molecular biology of different neuronal
cell populations. Current techniques to study enriched neurons in vitro are primarily limited …

RNAi-nanoparticulate manipulation of gene expression as a new functional genomics tool in the liver

H Yin, RL Bogorad, C Barnes, S Walsh, I Zhuang… - Journal of …, 2016 - Elsevier
Background & Aims The Hippo pathway controls organ size through a negative regulation
of the transcription co-activator Yap1. The overexpression of hyperactive mutant Yap1 or …

Retinal hemorrhages in a patient with petechiae

I Zhuang, I Gupta, CY Weng - JAMA ophthalmology, 2019 - jamanetwork.com
A 44-year-old man with a 2-week history of fevers, night sweats, chills, and petechiae presented
with painless, blurry vision in the left eye. His ocular symptoms began 2 days prior when …

Abducens nerve palsy and ipsilateral Horner syndrome as the presenting finding of carotid cavernous fistula

I Zhuang, A Kini, B Al Othman… - Canadian …, 2019 - canadianjournalofophthalmology.ca
D iscussion CCF is an abnormal connection between the ICA or ECA (or its branches) and
the cavernous sinus (CS) that can be classified based on etiology (eg, traumatic vs …

Iris recognition algorithm using modified log-gabor filters

P Yao, J Li, X Ye, Z Zhuang, B Li - … International Conference on …, 2006 - ieeexplore.ieee.org
… In this paper, we presented an iris recognition algorithm … adopted to extract the iris phase
information instead of complex … more suitable to extract the iris phase features regardless of the …

Driver fatigue detection method based on eye states with pupil and iris segmentation

Q Zhuang, Z Kehua, J Wang, Q Chen - Ieee Access, 2020 - ieeexplore.ieee.org
Fatigue driving has become one of the most common causes for traffic accidents. In this article,
we proposed an effective fatigue detection method based on eye status with pupil and iris

Iris recognition using convolutional neural network

Y Zhuang, JH Chuah, CO Chow… - 2020 IEEE 10th …, 2020 - ieeexplore.ieee.org
… to further elevate the penetration of iris recognition in safeguarding one's … iris recognition
system based on convolutional neural network with high precision and efficiency. A total of iris

Comparison of Rates of RNFL Change Between Two Optical Coherence Tomography Devices

I Zhuang, V Mohammadzadeh, A Yonge… - … & Visual Science, 2023 - iovs.arvojournals.org
Purpose: To compare rates of retinal nerve fiber layer (RNFL) thickness change between
two commercially available optical coherence tomography (OCT) devices. Methods: Ninety-five …