SARS-CoV-2 in an Immunocompromised Host This letter describes an immunocompromised
patient who had persistent infection with SARS-CoV-2 over a period of months, despite …

COVID-19, which is caused by SARS-CoV-2, can result in acute respiratory distress syndrome
and multiple organ failure 1 , 2 , 3 – 4 , but little is known about its pathophysiology. Here …

Brain Autopsy Series in Patients with Covid-19 Eighteen brains of patients who died 0 to 32
days after the onset of symptoms of SARS-CoV-2 infection showed hypoxic–ischemic …

Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 has led to a global public
health crisis. In elderly individuals and those with comorbidities, COVID-19 is associated with …

Human interleukin-12 (hIL-12) is a cytokine with anticancer activity, but its systemic application
is limited by toxic inflammatory responses. We assessed the safety and biological effects …

The human nuclear receptor liver receptor homolog 1 (hLRH-1) plays an important role in
the development of breast carcinomas. This orphan receptor is efficiently downregulated by …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
coronavirus disease 2019 (COVID-19) for which there have been over 50 million confirmed …

Objective To explore the spectrum of skeletal muscle and nerve pathology of patients who
died after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and to …

As coronavirus disease 2019 (COVID-19) and aging are both accompanied by cognitive
decline, we hypothesized that COVID-19 might lead to molecular signatures similar to aging. …

Methods| The institutional review boards of Johns Hopkins University and Mass General
Brigham approved this study, and the next of kin of each patient consented for use of tissues for …