Preeclampsia, a syndrome affecting 5% of pregnancies, causes substantial maternal and fetal
morbidity and mortality. The pathophysiology of preeclampsia remains largely unknown. It …

Preeclampsia is a pregnancy-specific hypertensive syndrome that causes substantial maternal
and fetal morbidity and mortality. Maternal endothelial dysfunction mediated by excess …

Double negative (DN) T cells are expanded in patients with systemic lupus erythematosus (SLE)
and stimulate autoantibody production as efficiently as CD4+ T cells. In this study, we …

Replication-deficient adenoviruses are known to induce acute injury and inflammation of
infected tissues, thus limiting their use for human gene therapy. However, molecular …

Preeclampsia: A renal perspective. Preeclampsia is a syndrome that affects 5% of all
pregnancies, producing substantial maternal and perinatal morbidity and mortality. The aim of this …

Sepsis-associated acute kidney injury (AKI) is a common and morbid condition that is
distinguishable from typical ischemic renal injury by its paucity of tubular cell death. The …

Vascular basement membrane is an important structural component of blood vessels.
During angiogenesis this membrane undergoes many alterations and these changes are …

The energetic burden of continuously concentrating solutes against gradients along the
tubule may render the kidney especially vulnerable to ischaemia. Acute kidney injury (AKI) …

Preeclampsia is a pregnancy-specific disorder that complicates approximately 5% of all
pregnancies, making it perhaps the most common glomerular disease in the world. It is …

Diabetic nephropathy (DN) is a major cause of end-stage renal disease, and therapeutic
options for preventing its progression are limited. To identify novel therapeutic strategies, we …